Intestinal and Nonintestinal Cancer Risks for Patients with Crohn's Disease

Sushil K. Garg, Fernando S. Velayos, John B Kisiel

Research output: Contribution to journalReview article

3 Scopus citations

Abstract

Crohn's disease (CD) is a chronic inflammatory disease that confers a higher risk of cancer than in the general population. New, large, population-based studies in the past decade show that patients with CD are at higher risk of colorectal, small bowel, melanoma, and cervical cancer. Patients who use thiopurines are at additional risk of development of lymphoma and nonmelanoma skin cancer. Preventive surveillance for cancers of the colorectum, skin, and uterine cervix is advised.

Original languageEnglish (US)
Pages (from-to)515-529
Number of pages15
JournalGastroenterology Clinics of North America
Volume46
Issue number3
DOIs
StatePublished - Sep 1 2017

Keywords

  • 6-mercaptopurine/adverse effects
  • Colorectal neoplasms
  • Inflammatory bowel diseases
  • Lymphoma
  • Monoclonal antibodies/adverse effects
  • Skin neoplasms/secondary

ASJC Scopus subject areas

  • Gastroenterology

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