TY - JOUR
T1 - Intestinal and Nonintestinal Cancer Risks for Patients with Crohn's Disease
AU - Garg, Sushil K.
AU - Velayos, Fernando S.
AU - Kisiel, John B.
N1 - Publisher Copyright:
© 2017 Elsevier Inc.
PY - 2017/9
Y1 - 2017/9
N2 - Crohn's disease (CD) is a chronic inflammatory disease that confers a higher risk of cancer than in the general population. New, large, population-based studies in the past decade show that patients with CD are at higher risk of colorectal, small bowel, melanoma, and cervical cancer. Patients who use thiopurines are at additional risk of development of lymphoma and nonmelanoma skin cancer. Preventive surveillance for cancers of the colorectum, skin, and uterine cervix is advised.
AB - Crohn's disease (CD) is a chronic inflammatory disease that confers a higher risk of cancer than in the general population. New, large, population-based studies in the past decade show that patients with CD are at higher risk of colorectal, small bowel, melanoma, and cervical cancer. Patients who use thiopurines are at additional risk of development of lymphoma and nonmelanoma skin cancer. Preventive surveillance for cancers of the colorectum, skin, and uterine cervix is advised.
KW - 6-mercaptopurine/adverse effects
KW - Colorectal neoplasms
KW - Inflammatory bowel diseases
KW - Lymphoma
KW - Monoclonal antibodies/adverse effects
KW - Skin neoplasms/secondary
UR - http://www.scopus.com/inward/record.url?scp=85028630262&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85028630262&partnerID=8YFLogxK
U2 - 10.1016/j.gtc.2017.05.006
DO - 10.1016/j.gtc.2017.05.006
M3 - Review article
C2 - 28838412
AN - SCOPUS:85028630262
SN - 0889-8553
VL - 46
SP - 515
EP - 529
JO - Gastroenterology Clinics of North America
JF - Gastroenterology Clinics of North America
IS - 3
ER -