Interventions for mesenteric vasculitis

Yevgeniy Rits, Gustavo Oderich, Thomas C. Bower, Dylan V. Miller, Leslie T Jr. Cooper, Joseph J. Ricotta, Manju Kalra, Peter Gloviczki

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Objective: This study reviewed the outcomes of open and endovascular revascularization for mesenteric vasculitis (MV). Methods: We reviewed the clinical data of all patients who underwent revascularization for occlusive MV from 1984 to 2008. Patients treated for aneurysms or mucosal bleeding without ischemic symptoms were excluded. End points were early mortality and morbidity, survival, freedom from mesenteric symptoms, and patency. Outcomes of open reconstructions were compared with the results of 163 patients who underwent open operations for atherosclerotic disease. Results: There were 15 patients (13 females, 2 males) with a mean age of 38 years (range, 15-66 years). Etiologies were Takayasu's arteritis in 7, polyarteritis nodosa in 4, indeterminate in 3, and giant cell arteritis in 1. The celiac axis was affected in 13, superior mesenteric artery (SMA) in 13, renal arteries in 8, and the aorta in 4. Seven patients had active disease, and eight were in remission. Nine (60%) presented with symptomatic chronic (n = 8) and acute (n = 1) mesenteric ischemia. Six patients with asymptomatic disease underwent mesenteric revascularization during other aortic-based operations. Fourteen patients (93%) had 10 mesenteric bypasses (8 aortic based; 2 iliac), three had aortoplasties, of which two had mesenteric patch angioplasties, and one underwent arcuate ligament release with patch angioplasty. One patient (7%) underwent percutaneous transluminal angioplasty of SMA stenosis. There were no early deaths. Early complications occurred in three patients (20%) after open reconstruction, including gastrointestinal hemorrhage, ileus with re-exploration, and superior mesenteric vein thrombosis. Median follow-up was 22 months. One graft thrombosis in a patient with active disease was treated with redo bypass 74 months after aorta-celiac-SMA bypass. All patients were alive at 10 years, with similar expected survival compared with the general population (P = .69). Compared with patients with atherosclerotic disease, open reconstructions for MV had similar freedom from mesenteric symptoms (83% vs 75%, P = .80) and similar primary graft patency (83% vs 84%, P = .9). Conclusion: Mesenteric vasculitis is a rare manifestation of Takayasu arteritis, polyarteritis nodosa, indeterminate, or giant cell arteritis. Open revascularization is durable and effective when needed.

Original languageEnglish (US)
JournalJournal of Vascular Surgery
Volume51
Issue number2
DOIs
StatePublished - Feb 2010

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Vasculitis
Superior Mesenteric Artery
Angioplasty
Takayasu Arteritis
Polyarteritis Nodosa
Giant Cell Arteritis
Abdomen
Aorta
Thrombosis
Transplants
Asymptomatic Diseases
Mesenteric Veins
Gastrointestinal Hemorrhage
Survival
Ileus
Renal Artery
Ligaments
Aneurysm
Pathologic Constriction
Outcome Assessment (Health Care)

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery

Cite this

Rits, Y., Oderich, G., Bower, T. C., Miller, D. V., Cooper, L. T. J., Ricotta, J. J., ... Gloviczki, P. (2010). Interventions for mesenteric vasculitis. Journal of Vascular Surgery, 51(2). https://doi.org/10.1016/j.jvs.2009.08.082

Interventions for mesenteric vasculitis. / Rits, Yevgeniy; Oderich, Gustavo; Bower, Thomas C.; Miller, Dylan V.; Cooper, Leslie T Jr.; Ricotta, Joseph J.; Kalra, Manju; Gloviczki, Peter.

In: Journal of Vascular Surgery, Vol. 51, No. 2, 02.2010.

Research output: Contribution to journalArticle

Rits, Y, Oderich, G, Bower, TC, Miller, DV, Cooper, LTJ, Ricotta, JJ, Kalra, M & Gloviczki, P 2010, 'Interventions for mesenteric vasculitis', Journal of Vascular Surgery, vol. 51, no. 2. https://doi.org/10.1016/j.jvs.2009.08.082
Rits, Yevgeniy ; Oderich, Gustavo ; Bower, Thomas C. ; Miller, Dylan V. ; Cooper, Leslie T Jr. ; Ricotta, Joseph J. ; Kalra, Manju ; Gloviczki, Peter. / Interventions for mesenteric vasculitis. In: Journal of Vascular Surgery. 2010 ; Vol. 51, No. 2.
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abstract = "Objective: This study reviewed the outcomes of open and endovascular revascularization for mesenteric vasculitis (MV). Methods: We reviewed the clinical data of all patients who underwent revascularization for occlusive MV from 1984 to 2008. Patients treated for aneurysms or mucosal bleeding without ischemic symptoms were excluded. End points were early mortality and morbidity, survival, freedom from mesenteric symptoms, and patency. Outcomes of open reconstructions were compared with the results of 163 patients who underwent open operations for atherosclerotic disease. Results: There were 15 patients (13 females, 2 males) with a mean age of 38 years (range, 15-66 years). Etiologies were Takayasu's arteritis in 7, polyarteritis nodosa in 4, indeterminate in 3, and giant cell arteritis in 1. The celiac axis was affected in 13, superior mesenteric artery (SMA) in 13, renal arteries in 8, and the aorta in 4. Seven patients had active disease, and eight were in remission. Nine (60{\%}) presented with symptomatic chronic (n = 8) and acute (n = 1) mesenteric ischemia. Six patients with asymptomatic disease underwent mesenteric revascularization during other aortic-based operations. Fourteen patients (93{\%}) had 10 mesenteric bypasses (8 aortic based; 2 iliac), three had aortoplasties, of which two had mesenteric patch angioplasties, and one underwent arcuate ligament release with patch angioplasty. One patient (7{\%}) underwent percutaneous transluminal angioplasty of SMA stenosis. There were no early deaths. Early complications occurred in three patients (20{\%}) after open reconstruction, including gastrointestinal hemorrhage, ileus with re-exploration, and superior mesenteric vein thrombosis. Median follow-up was 22 months. One graft thrombosis in a patient with active disease was treated with redo bypass 74 months after aorta-celiac-SMA bypass. All patients were alive at 10 years, with similar expected survival compared with the general population (P = .69). Compared with patients with atherosclerotic disease, open reconstructions for MV had similar freedom from mesenteric symptoms (83{\%} vs 75{\%}, P = .80) and similar primary graft patency (83{\%} vs 84{\%}, P = .9). Conclusion: Mesenteric vasculitis is a rare manifestation of Takayasu arteritis, polyarteritis nodosa, indeterminate, or giant cell arteritis. Open revascularization is durable and effective when needed.",
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N2 - Objective: This study reviewed the outcomes of open and endovascular revascularization for mesenteric vasculitis (MV). Methods: We reviewed the clinical data of all patients who underwent revascularization for occlusive MV from 1984 to 2008. Patients treated for aneurysms or mucosal bleeding without ischemic symptoms were excluded. End points were early mortality and morbidity, survival, freedom from mesenteric symptoms, and patency. Outcomes of open reconstructions were compared with the results of 163 patients who underwent open operations for atherosclerotic disease. Results: There were 15 patients (13 females, 2 males) with a mean age of 38 years (range, 15-66 years). Etiologies were Takayasu's arteritis in 7, polyarteritis nodosa in 4, indeterminate in 3, and giant cell arteritis in 1. The celiac axis was affected in 13, superior mesenteric artery (SMA) in 13, renal arteries in 8, and the aorta in 4. Seven patients had active disease, and eight were in remission. Nine (60%) presented with symptomatic chronic (n = 8) and acute (n = 1) mesenteric ischemia. Six patients with asymptomatic disease underwent mesenteric revascularization during other aortic-based operations. Fourteen patients (93%) had 10 mesenteric bypasses (8 aortic based; 2 iliac), three had aortoplasties, of which two had mesenteric patch angioplasties, and one underwent arcuate ligament release with patch angioplasty. One patient (7%) underwent percutaneous transluminal angioplasty of SMA stenosis. There were no early deaths. Early complications occurred in three patients (20%) after open reconstruction, including gastrointestinal hemorrhage, ileus with re-exploration, and superior mesenteric vein thrombosis. Median follow-up was 22 months. One graft thrombosis in a patient with active disease was treated with redo bypass 74 months after aorta-celiac-SMA bypass. All patients were alive at 10 years, with similar expected survival compared with the general population (P = .69). Compared with patients with atherosclerotic disease, open reconstructions for MV had similar freedom from mesenteric symptoms (83% vs 75%, P = .80) and similar primary graft patency (83% vs 84%, P = .9). Conclusion: Mesenteric vasculitis is a rare manifestation of Takayasu arteritis, polyarteritis nodosa, indeterminate, or giant cell arteritis. Open revascularization is durable and effective when needed.

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