Interstitial pneumonitis associated with 'crack' cocaine abuse

A. E. O'Donnell; F. G. Mappin; T. J. Sebo; H. Tazelaar

doi:10.1378/chest.100.4.1155

Interstitial pneumonitis associated with 'crack' cocaine abuse

A. E. O'Donnell, F. G. Mappin, T. J. Sebo, H. Tazelaar

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41 Scopus citations

Abstract

A 33-year-old woman developed acute bilateral pulmonary infiltrates after the intense use of rock cocaine (crack). She subsequently had progressive deterioration of pulmonary function to the point of being ventilator-dependent. Open lung biopsy showed a chronic interstitial pneumonia with extensive accumulation of free silica within histiocytes associated with mild pulmonary fibrosis. This pattern of interstitial pneumonia has not been previously reported in crack users.

Original language	English (US)
Pages (from-to)	1155-1157
Number of pages	3
Journal	Chest
Volume	100
Issue number	4
DOIs	https://doi.org/10.1378/chest.100.4.1155
State	Published - 1991

ASJC Scopus subject areas

Pulmonary and Respiratory Medicine
Critical Care and Intensive Care Medicine
Cardiology and Cardiovascular Medicine

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10.1378/chest.100.4.1155

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title = "Interstitial pneumonitis associated with 'crack' cocaine abuse",

abstract = "A 33-year-old woman developed acute bilateral pulmonary infiltrates after the intense use of rock cocaine (crack). She subsequently had progressive deterioration of pulmonary function to the point of being ventilator-dependent. Open lung biopsy showed a chronic interstitial pneumonia with extensive accumulation of free silica within histiocytes associated with mild pulmonary fibrosis. This pattern of interstitial pneumonia has not been previously reported in crack users.",

author = "O'Donnell, {A. E.} and Mappin, {F. G.} and Sebo, {T. J.} and H. Tazelaar",

year = "1991",

doi = "10.1378/chest.100.4.1155",

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AU - O'Donnell, A. E.

AU - Mappin, F. G.

AU - Sebo, T. J.

AU - Tazelaar, H.

PY - 1991

Y1 - 1991

N2 - A 33-year-old woman developed acute bilateral pulmonary infiltrates after the intense use of rock cocaine (crack). She subsequently had progressive deterioration of pulmonary function to the point of being ventilator-dependent. Open lung biopsy showed a chronic interstitial pneumonia with extensive accumulation of free silica within histiocytes associated with mild pulmonary fibrosis. This pattern of interstitial pneumonia has not been previously reported in crack users.

AB - A 33-year-old woman developed acute bilateral pulmonary infiltrates after the intense use of rock cocaine (crack). She subsequently had progressive deterioration of pulmonary function to the point of being ventilator-dependent. Open lung biopsy showed a chronic interstitial pneumonia with extensive accumulation of free silica within histiocytes associated with mild pulmonary fibrosis. This pattern of interstitial pneumonia has not been previously reported in crack users.

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Interstitial pneumonitis associated with 'crack' cocaine abuse

Abstract

ASJC Scopus subject areas

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