Interstitial lung disease in rheumatoid arthritis

Kristine Phillips, Kevin R. Flaherty, Eric L. Matteson, Tim Bongartz, Joan Bathon, Kevin K. Brown, Paul F. Dellaripa

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Rheumatoid arthritis (RA) affects 1-2% of the general population. Although often thought of as primarily a localized inflammatory disorder with associated joint destruction, it is a diffuse systemic disease. Extra-articular manifestations of rheumatoid arthritis can be demonstrated in almost 50% of patients with RA, and include pulmonary, cardiac, ocular, renal, hematologic, and neurologic involvement. In this article, we review recent studies of interstitial lung disease (ILD) in RA with a focus on clinical and pathological features of rheumatoid arthritis associated interstitial lung disease (RA-ILD). We discuss an approach to the diagnosis and treatment of RA-ILD including potential biomarkers, and conclude by outlining areas for future research.

Original languageEnglish (US)
Pages (from-to)120-126
Number of pages7
JournalCurrent Rheumatology Reviews
Volume6
Issue number2
DOIs
StatePublished - Sep 20 2010

Keywords

  • Interstitial lung disease
  • Pulmonary fibrosis
  • Rheumatoid arthritis

ASJC Scopus subject areas

  • Rheumatology

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