Interleukin 2, production in the syngeneic mixed lymphocyte reaction

Edmund C. Lattime, Steven Gillis, Chella David, Osias Stutman

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

In the syngeneic mixed lymphocyte reaction, Ly 1 cells proliferate following stimulation with Ia‐positive macrophage‐like cells. The proliferation is accompanied by the release of interleukin 2 into the medium. Both the proliferation and interleukin 2 production are dependent on the expression of Ia antigenic determinants, as the addition of haplotype‐specific anti‐Ia antisera to the cultures inhibits both parameters.

Original languageEnglish (US)
Pages (from-to)67-69
Number of pages3
JournalEuropean Journal of Immunology
Volume11
Issue number1
DOIs
StatePublished - Jan 1 1981
Externally publishedYes

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Mixed Lymphocyte Culture Test
Interleukin-2
Immune Sera
Epitopes

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

Cite this

Interleukin 2, production in the syngeneic mixed lymphocyte reaction. / Lattime, Edmund C.; Gillis, Steven; David, Chella; Stutman, Osias.

In: European Journal of Immunology, Vol. 11, No. 1, 01.01.1981, p. 67-69.

Research output: Contribution to journalArticle

Lattime, Edmund C. ; Gillis, Steven ; David, Chella ; Stutman, Osias. / Interleukin 2, production in the syngeneic mixed lymphocyte reaction. In: European Journal of Immunology. 1981 ; Vol. 11, No. 1. pp. 67-69.
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