Integration of Radiation Oncology with Surgery as Combined-Modality Treatment

Leonard L. Gunderson; Jonathan B. Ashman; Michael G. Haddock; Ivy A. Petersen; Adyr Moss; Jacques Heppell; Richard J. Gray; Barbara A. Pockaj; Heidi Nelson; Christopher Beauchamp

doi:10.1016/j.soc.2013.02.003

Integration of Radiation Oncology with Surgery as Combined-Modality Treatment

Leonard L. Gunderson, Jonathan B. Ashman, Michael G. Haddock, Ivy A. Petersen, Adyr Moss, Jacques Heppell, Richard J. Gray, Barbara A. Pockaj, Heidi Nelson, Christopher Beauchamp

Research output: Contribution to journal › Review article › peer-review

7 Scopus citations

Abstract

Integration of surgery and radiation (external beam, EBRT; intraoperative, IORT) has become more routine for patients with locally advanced primary cancers and those with local-regional relapse. This article discusses patient selection and treatment from a more general perspective, followed by a discussion of patient selection and treatment factors in select disease sites (pancreas cancer, colorectal cancer, retroperitoneal soft-tissue sarcomas). Outcomes with combined modality treatment (surgery, EBRT alone or with concurrent chemotherapy, IORT) are discussed. The ultimate in contemporary integration of radiation and surgery is found in patients who are candidates for surgery plus both EBRT and IORT.

Original language	English (US)
Pages (from-to)	405-432
Number of pages	28
Journal	Surgical Oncology Clinics of North America
Volume	22
Issue number	3
DOIs	https://doi.org/10.1016/j.soc.2013.02.003
State	Published - Jul 1 2013

Keywords

Combined modality treatment
Intraoperative radiation
Patient selection criteria
Surgery and radiation integration

ASJC Scopus subject areas

Surgery
Oncology

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10.1016/j.soc.2013.02.003

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title = "Integration of Radiation Oncology with Surgery as Combined-Modality Treatment",

abstract = "Integration of surgery and radiation (external beam, EBRT; intraoperative, IORT) has become more routine for patients with locally advanced primary cancers and those with local-regional relapse. This article discusses patient selection and treatment from a more general perspective, followed by a discussion of patient selection and treatment factors in select disease sites (pancreas cancer, colorectal cancer, retroperitoneal soft-tissue sarcomas). Outcomes with combined modality treatment (surgery, EBRT alone or with concurrent chemotherapy, IORT) are discussed. The ultimate in contemporary integration of radiation and surgery is found in patients who are candidates for surgery plus both EBRT and IORT.",

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author = "Gunderson, {Leonard L.} and Ashman, {Jonathan B.} and Haddock, {Michael G.} and Petersen, {Ivy A.} and Adyr Moss and Jacques Heppell and Gray, {Richard J.} and Pockaj, {Barbara A.} and Heidi Nelson and Christopher Beauchamp",

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AU - Gunderson, Leonard L.

AU - Ashman, Jonathan B.

AU - Haddock, Michael G.

AU - Petersen, Ivy A.

AU - Moss, Adyr

AU - Heppell, Jacques

AU - Gray, Richard J.

AU - Pockaj, Barbara A.

AU - Nelson, Heidi

AU - Beauchamp, Christopher

PY - 2013/7/1

Y1 - 2013/7/1

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AB - Integration of surgery and radiation (external beam, EBRT; intraoperative, IORT) has become more routine for patients with locally advanced primary cancers and those with local-regional relapse. This article discusses patient selection and treatment from a more general perspective, followed by a discussion of patient selection and treatment factors in select disease sites (pancreas cancer, colorectal cancer, retroperitoneal soft-tissue sarcomas). Outcomes with combined modality treatment (surgery, EBRT alone or with concurrent chemotherapy, IORT) are discussed. The ultimate in contemporary integration of radiation and surgery is found in patients who are candidates for surgery plus both EBRT and IORT.

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KW - Intraoperative radiation

KW - Patient selection criteria

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Integration of Radiation Oncology with Surgery as Combined-Modality Treatment

Abstract

Keywords

ASJC Scopus subject areas

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