Integration of functional assay data results provides strong evidence for classification of hundreds of BRCA1 variants of uncertain significance

Paulo C.M. Lyra, Thales C. Nepomuceno, Marcele L.M. de Souza, Géssica F. Machado, Mariana F. Veloso, Taciane B. Henriques, Diandra Z. dos Santos, Iuly G. Ribeiro, Roberto S. Ribeiro, Leticia B.A. Rangel, Marcy Richardson, Edwin S. Iversen, David Goldgar, Fergus J. Couch, Marcelo A. Carvalho, Alvaro N.A. Monteiro

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Medicine & Life Sciences