Integratingva's NDF-RT drug terminology with PharmGKB: Preliminary results

Jyotishman Pathak, Laura C. Weiss, Matthew J. Durski, Qian Zhu, Robert R. Freimuth, Christopher G. Chute

Research output: Contribution to journalConference articlepeer-review

3 Scopus citations

Abstract

Biomedical terminology and vocabulary standards play an important role in enabling consistent, comparable, and meaningful sharing of data within and across institutional boundaries, as well as ensuring semantic interoperability. The Veterans Affairs (VA) National Drug File Reference Terminology (NDF-RT) is a federally recommended standardized terminology resource encompassing medications, ingredients, and a hierarchy for high-level drug classes. In this study, we investigate the drug-disease relationships in NDF-RT and determine how PharmGKB can be leveraged to augment NDF-RT, and viceversa. Our preliminary results indicate that with additional curation and analyses, information contained in both knowledge resources can be mutually integrated.

Original languageEnglish (US)
Pages (from-to)400-409
Number of pages10
JournalPacific Symposium on Biocomputing
StatePublished - 2012
Event17th Pacific Symposium on Biocomputing, PSB 2012 - Kohala Coast, United States
Duration: Jan 3 2012Jan 7 2012

ASJC Scopus subject areas

  • Biomedical Engineering
  • Computational Theory and Mathematics

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