Insulinoma in chronic renal failure: A case report

Ananda Basu, Michael T. Sheehan, Geoffrey B. Thompson, F. J. Service

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

The diagnosis of insulinoma depends on the fulfillment of well-established criteria during the 72-h fast. However, these criteria rely on normal renal function. Spontaneous hypoglycemia that is not attributable to insulinoma may occur in persons with renal failure. We describe herein a patient with renal impairment who had undergone renal transplant and had a 20-yr history of hypoglycemic symptoms and successful resection of insulinoma. Although the results of a 72-h fast were consistent with endogenous hyperinsulinemia, their interpretation was complicated in the presence of renal impairment. Fortunately, the identification of the tumor, by endoscopic ultrasonograph, led to a correct diagnosis. This case seems to be the second report of a patient with insulinoma with concomitant renal failure.

Original languageEnglish (US)
Pages (from-to)4889-4891
Number of pages3
JournalJournal of Clinical Endocrinology and Metabolism
Volume87
Issue number11
DOIs
StatePublished - Nov 1 2002

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Biochemistry
  • Endocrinology
  • Clinical Biochemistry
  • Biochemistry, medical

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