Insulin deficiency and intranasal insulin alter brain mitochondrial function: a potential factor for dementia in diabetes

Medicine & Life Sciences

• Dementia 51%
• Insulin 42%
• Brain 30%
• Adenosine Triphosphate 12%
• Cerebrum 11%
• Reactive Oxygen Species 8%
• Mitochondrial Proton-Translocating ATPases 8%
• Citrate (si)-Synthase 6%
• Mitochondrial Dynamics 6%
• Intranasal Administration 6%
• Ketones 6%
• Electron Transport Complex IV 6%
• Mitochondrial Proteins 5%
• Post Translational Protein Processing 5%
• Streptozocin 5%
• Synaptic Transmission 4%
• Hypothalamus 4%
• Proteomics 4%
• Lactic Acid 4%
• Psychological Inhibition 4%
• Hippocampus 4%
• Oxidative Stress 3%
• Homeostasis 3%
• Phosphorylation 3%
• Proteins 1%
• Therapeutics 0%

Chemical Compounds

• Intranasal 100%
• Insulin Derivative 63%
• Reactive Oxygen Metabolite 9%
• Protein 6%
• Fission 5%
• Lactate 5%
• Oxidative Stress 5%
• Cytochrome 4%
• Fuel 4%
• Modification 2%