Instrument to detect syncope and the onset of shock

Daniel R. McAdams, Noah J. Kolodziejski, Christopher J. Stapels, Daniel E. Fernandez, Matthew J. Podolsky, Dana Farkas, James F. Christian, Michael J. Joyner, Christopher P. Johnson, Norman A. Paradis

Research output: Chapter in Book/Report/Conference proceedingConference contribution

6 Scopus citations

Abstract

Currently the diagnosis of hemorrhagic shock is essentially clinical, relying on the expertise of nurses and doctors. One of the first measurable physiological changes that marks the onset of hemorrhagic shock is a decrease in capillary blood flow. Diffuse correlation spectroscopy (DCS) quantifies this decrease. DCS collects and analyzes multiply scattered, coherent, near infrared light to assess relative blood flow. This work presents a preliminary study using a DCS instrument with human subjects undergoing a lower body negative pressure (LBNP) protocol. This work builds on previous successful DCS instrumentation development and we believe it represents progress toward understanding how DCS can be used in a clinical setting.

Original languageEnglish (US)
Title of host publicationDynamics and Fluctuations in Biomedical Photonics XIII
EditorsValery V. Tuchin, Martin J. Leahy, Kirill V. Larin, Valery V. Tuchin, Ruikang K. Wang
PublisherSPIE
ISBN (Electronic)9781628419412
DOIs
StatePublished - 2016
EventDynamics and Fluctuations in Biomedical Photonics XIII Conference - San Francisco, United States
Duration: Feb 14 2016Feb 15 2016

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume9707
ISSN (Print)1605-7422

Other

OtherDynamics and Fluctuations in Biomedical Photonics XIII Conference
CountryUnited States
CitySan Francisco
Period2/14/162/15/16

Keywords

  • Diffuse correlation spectroscopy
  • capillary blood flow monitoring
  • hemorrhagic shock
  • microcirculation
  • multiple-scattering
  • speckle

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

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