Insertional mutagenesis strategies in zebrafish

Sridhar Sivasubbu, Darius Balciunas, Adam Amsterdam, Stephen C. Ekker

Research output: Contribution to journalReview article

46 Scopus citations

Abstract

We review here some recent developments in the field of insertional mutagenesis in zebrafish. We highlight the advantages and limitations of the rich body of retroviral methodologies, and we focus on the mechanisms and concepts of new transposon-based mutagenesis approaches under development, including prospects for conditional 'gene trapping' and 'gene breaking' approaches.

Original languageEnglish (US)
Article numberS9
JournalGenome biology
Volume8
Issue numberSUPPL. 1
DOIs
StatePublished - Oct 31 2007

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Genetics
  • Cell Biology

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