Abstract
We provide an overview of the latest developments in cancer gene therapy - from the bench to early-stage clinical trials. We describe the most recent work of worldwide teams including experienced scientists and clinicians, reflecting the recent emergence of gene therapy from the 'Valley of Death'. treatment efficacy of clinical gene therapy has now been shown in a number of diseases including cancer and we are observing a renewed interest by big pharmaceutical and biotechnology companies most obviously demonstrated by Amgen's acquisition of Biovex for up to USD$1 billion. There is an opportunity to be cautiously hopeful regarding the future of gene therapy in the clinic and we review here some of the most recent progress in the field.
Original language | English (US) |
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Pages (from-to) | 141-149 |
Number of pages | 9 |
Journal | Cancer Gene Therapy |
Volume | 20 |
Issue number | 3 |
DOIs | |
State | Published - Mar 2013 |
Keywords
- cancer research
- immunotherapy
- stem cells
ASJC Scopus subject areas
- Molecular Medicine
- Molecular Biology
- Cancer Research