Injection of (99m)Tc-labeled sulfur colloid the day before operation for breast cancer sentinel lymph node mapping is as successful as injection the day of operation.

Richard J. Gray, Barbara A. Pockaj, Michael C. Roarke

Research output: Contribution to journalArticle

20 Scopus citations

Abstract

BACKGROUND: We investigated whether the timing of injection of (99m)Tc-labeled sulfur colloid (radiocolloid) significantly influenced the success of breast cancer sentinel lymph node (SLN) mapping. METHODS: Review of a prospective SLN database. Five hundred forty-six consecutive breast SLN mapping patients were analyzed. A dual radiocolloid/blue dye technique was used in all patients. RESULTS: The SLN identification rate was similar among those patients injected the day prior (100%) and those injected the day of operation (99%, P = 0.14). A "hot" SLN was identified in 99% of patients injected the day prior and in 97% (P = 0.17) injected the day of operation. The mean number of SLNs was greater among those injected the day prior (2.71) than among those injected the day of operation (2.33, P = 0.01). There were no differences in the rates of SLN metastases. CONCLUSIONS: Radiocolloid injection the day before operation is an acceptable and logistically advantageous technique for breast cancer SLN mapping.

Original languageEnglish (US)
Pages (from-to)685-689
Number of pages5
JournalAmerican journal of surgery
Volume188
Issue number6
DOIs
StatePublished - Dec 2004

ASJC Scopus subject areas

  • Surgery

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