@article{749083ae80344e24a53d4c2d89c4e450,
title = "Initial Therapeutic Approaches to Patients with Multiple Myeloma",
abstract = "Multiple Myeloma (MM) is part of a spectrum of plasma cell disorders that may result in end organ damage. MM is subclassified into high and standard risk based on cytogenetic and laboratory markers. The treatment of newly diagnosed multiple myeloma is constantly changing with the advent of novel therapies. Recent advances in therapies have resulted in longer time to remission and overall survival. the introduction of targeted therapy with monoclonal antibodies such as Daratumumab has improved stringent complete response to 39%. In this review, we outline the current approach to diagnosis, prognosis, and management of newly diagnosed multiple myeloma in both transplant eligible and ineligible patients",
keywords = "Multiple myeloma, Therapeutic approaches",
author = "Berbari, {Hadi E.} and Kumar, {Shaji K.}",
note = "Funding Information: No funding or sponsorship was received for this study or publication of this article. All named authors meet the International Committee of Medical Journal Editors (ICMJE) criteria for authorship take responsibility for the integrity of the work as a whole, and have given their approval for this version to be published. Both authors have equally contributed to the final paper, performed the review of the papers as well as drafting of the manuscript. Hadi Berbari and Shaji Kumar have no conflicts of interest to declare. This article is based on previously conducted studies and does not contain any new studies with human participants or animals performed by any of the authors. Data sharing is not applicable to this article as no datasets were generated or analyzed during the current study. Publisher Copyright: {\textcopyright} 2021, The Author(s), under exclusive licence to Springer Healthcare Ltd., part of Springer Nature.",
year = "2021",
month = jul,
doi = "10.1007/s12325-021-01824-5",
language = "English (US)",
volume = "38",
pages = "3694--3711",
journal = "Advances in Therapy",
issn = "0741-238X",
publisher = "Health Communications Inc.",
number = "7",
}