Initial clinical experience in MR imaging of the brain with a fast fluid- attenuated inversion-recovery pulse sequence

J. N. Rydberg, C. A. Hammond, R. C. Grimm, Bradley J Erickson, Clifford R Jr. Jack, John III Huston, Stephen J Riederer

Research output: Contribution to journalArticle

253 Citations (Scopus)

Abstract

PURPOSE: To evaluate fast fluid-attenuated inversion-recovery (FLAIR) technique for imaging brain abnormalities. MATERIALS AND METHODS: A fast FLAIR sequence was developed that provided 36 5-mm contiguous sections in 5 minutes 8 seconds. Resulting images were compared with dual-echo T2-weighted spin-echo images of 41 consecutive patients with brain abnormalities. RESULTS: Contrast and contrast-to-noise ratios (C/Ns) (for contrast between the lesion and background and between the lesion and cerebrospinal fluid) for fast FLAIR exceeded the corresponding values for T2-weighted spin-echo images for all but the second-echo lesion-to-background C/N. Fast FLAIR provided equivalent or greater overall lesion conspicuity and enabled greater lesion detection in 98% and 100%, respectively, of the evaluations. Fast FLAIR images more often had image artifact, but this did not interfere with image interpretation in a significantly (P ≤ .05) greater number of evaluations. CONCLUSION: Fast FLAIR provides images that are superior to proton-density- and T2-weighted images for many image quality criteria.

Original languageEnglish (US)
Pages (from-to)173-180
Number of pages8
JournalRadiology
Volume193
Issue number1
StatePublished - 1994

Fingerprint

Neuroimaging
Sequence Inversion
Artifacts
Cerebrospinal Fluid
Noise
Protons
Brain

Keywords

  • Brain, abnormalities
  • Brain, MR
  • Magnetic resonance (MR), pulse sequences

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

Cite this

Initial clinical experience in MR imaging of the brain with a fast fluid- attenuated inversion-recovery pulse sequence. / Rydberg, J. N.; Hammond, C. A.; Grimm, R. C.; Erickson, Bradley J; Jack, Clifford R Jr.; Huston, John III; Riederer, Stephen J.

In: Radiology, Vol. 193, No. 1, 1994, p. 173-180.

Research output: Contribution to journalArticle

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AU - Hammond, C. A.

AU - Grimm, R. C.

AU - Erickson, Bradley J

AU - Jack, Clifford R Jr.

AU - Huston, John III

AU - Riederer, Stephen J

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AB - PURPOSE: To evaluate fast fluid-attenuated inversion-recovery (FLAIR) technique for imaging brain abnormalities. MATERIALS AND METHODS: A fast FLAIR sequence was developed that provided 36 5-mm contiguous sections in 5 minutes 8 seconds. Resulting images were compared with dual-echo T2-weighted spin-echo images of 41 consecutive patients with brain abnormalities. RESULTS: Contrast and contrast-to-noise ratios (C/Ns) (for contrast between the lesion and background and between the lesion and cerebrospinal fluid) for fast FLAIR exceeded the corresponding values for T2-weighted spin-echo images for all but the second-echo lesion-to-background C/N. Fast FLAIR provided equivalent or greater overall lesion conspicuity and enabled greater lesion detection in 98% and 100%, respectively, of the evaluations. Fast FLAIR images more often had image artifact, but this did not interfere with image interpretation in a significantly (P ≤ .05) greater number of evaluations. CONCLUSION: Fast FLAIR provides images that are superior to proton-density- and T2-weighted images for many image quality criteria.

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