Initial clinical experience in MR imaging of the brain with a fast fluid- attenuated inversion-recovery pulse sequence

J. N. Rydberg, C. A. Hammond, R. C. Grimm, B. J. Erickson, C. R. Jack, J. Huston, S. J. Riederer

Research output: Contribution to journalArticle

254 Scopus citations

Abstract

PURPOSE: To evaluate fast fluid-attenuated inversion-recovery (FLAIR) technique for imaging brain abnormalities. MATERIALS AND METHODS: A fast FLAIR sequence was developed that provided 36 5-mm contiguous sections in 5 minutes 8 seconds. Resulting images were compared with dual-echo T2-weighted spin-echo images of 41 consecutive patients with brain abnormalities. RESULTS: Contrast and contrast-to-noise ratios (C/Ns) (for contrast between the lesion and background and between the lesion and cerebrospinal fluid) for fast FLAIR exceeded the corresponding values for T2-weighted spin-echo images for all but the second-echo lesion-to-background C/N. Fast FLAIR provided equivalent or greater overall lesion conspicuity and enabled greater lesion detection in 98% and 100%, respectively, of the evaluations. Fast FLAIR images more often had image artifact, but this did not interfere with image interpretation in a significantly (P ≤ .05) greater number of evaluations. CONCLUSION: Fast FLAIR provides images that are superior to proton-density- and T2-weighted images for many image quality criteria.

Original languageEnglish (US)
Pages (from-to)173-180
Number of pages8
JournalRadiology
Volume193
Issue number1
StatePublished - Jan 1 1994

Keywords

  • Brain, MR
  • Brain, abnormalities
  • Magnetic resonance (MR), pulse sequences

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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