TY - JOUR
T1 - Initial clinical experience in MR imaging of the brain with a fast fluid-attenuated inversion-recovery pulse sequence
AU - Rydberg, John N.
AU - Hammond, Charlotte A.
AU - Grimm, Roger C.
AU - Erickson, Bradley J.
AU - Jack, Clifford R.
AU - Huston, John
AU - Riederer, Stephen J.
PY - 1994/10
Y1 - 1994/10
N2 - PURPOSE: To evaluate fast fluid-attenuated inversion-recovery (FLAIR) technique for imaging brain abnormalities. MATERIALS AND METHODS: A fast FLAIR sequence was developed that provided 36 5-mm contiguous sections in 5 minutes 8 seconds. Resulting images were compared with dual-echo T2-weighted spin-echo images of 41 consecutive patients with brain abnormalities. RESULTS: Contrast and contrast-tonoise ratios (C/Ns) (for contrast between the lesion and background and between the lesion and cerebrospinal fluid) for fast FLAIR exceeded the corresponding values for T2-weighted spin-echo images for all but the second-echo lesion-to-background C/N. Fast FLAIR provided equivalent or greater overall lesion conspicuity and enabled greater lesion detection in 98% and 100%, respectively, of the evaluations. Fast FLAIR images more often had image artifact, but this did not interfere with image interpretation in a significantly (P ≤ .05) greater number of evaluations. CONCLUSION: Fast FLAIR provides images that are superior to proton-density- and T2-weighted images for many image quality criteria.
AB - PURPOSE: To evaluate fast fluid-attenuated inversion-recovery (FLAIR) technique for imaging brain abnormalities. MATERIALS AND METHODS: A fast FLAIR sequence was developed that provided 36 5-mm contiguous sections in 5 minutes 8 seconds. Resulting images were compared with dual-echo T2-weighted spin-echo images of 41 consecutive patients with brain abnormalities. RESULTS: Contrast and contrast-tonoise ratios (C/Ns) (for contrast between the lesion and background and between the lesion and cerebrospinal fluid) for fast FLAIR exceeded the corresponding values for T2-weighted spin-echo images for all but the second-echo lesion-to-background C/N. Fast FLAIR provided equivalent or greater overall lesion conspicuity and enabled greater lesion detection in 98% and 100%, respectively, of the evaluations. Fast FLAIR images more often had image artifact, but this did not interfere with image interpretation in a significantly (P ≤ .05) greater number of evaluations. CONCLUSION: Fast FLAIR provides images that are superior to proton-density- and T2-weighted images for many image quality criteria.
KW - Brain, MR, 10.121413
KW - Brain, abnormalities, 10.30, 10.781, 10.871
KW - Magnetic resonance (MR), pulse sequences
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U2 - 10.1148/radiology.193.1.8090888
DO - 10.1148/radiology.193.1.8090888
M3 - Article
C2 - 8090888
AN - SCOPUS:0028025274
SN - 0033-8419
VL - 193
SP - 173
EP - 180
JO - Radiology
JF - Radiology
IS - 1
ER -