Inhibition of ‘jumping genes’ promotes healthy ageing

Bennett Childs; Jan van Deursen

doi:10.1038/d41586-018-07553-0

Inhibition of ‘jumping genes’ promotes healthy ageing

Bennett Childs, Jan van Deursen

Pediatric and Adolescent Medicine

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

DNA sequences called retrotransposons can copy themselves and reintegrate at new sites in the genome, causing damage. It now seems that inhibiting this process can prevent age-related health decline in mice.

Original language	English (US)
Pages (from-to)	46-48
Number of pages	3
Journal	Nature
Volume	566
Issue number	7742
DOIs	https://doi.org/10.1038/d41586-018-07553-0
State	Published - Feb 7 2019

Keywords

Ageing
Molecular biology
Physiology

ASJC Scopus subject areas

General

Access to Document

10.1038/d41586-018-07553-0

Cite this

@article{a3c9e0f0dae447f591daaeed3be50375,

title = "Inhibition of {\textquoteleft}jumping genes{\textquoteright} promotes healthy ageing",

abstract = "DNA sequences called retrotransposons can copy themselves and reintegrate at new sites in the genome, causing damage. It now seems that inhibiting this process can prevent age-related health decline in mice.",

keywords = "Ageing, Molecular biology, Physiology",

author = "Bennett Childs and {van Deursen}, Jan",

note = "Publisher Copyright: {\textcopyright} 2019, Nature.",

year = "2019",

month = feb,

day = "7",

doi = "10.1038/d41586-018-07553-0",

language = "English (US)",

volume = "566",

pages = "46--48",

journal = "Nature",

issn = "0028-0836",

publisher = "Nature Publishing Group",

number = "7742",

}

TY - JOUR

T1 - Inhibition of ‘jumping genes’ promotes healthy ageing

AU - Childs, Bennett

AU - van Deursen, Jan

PY - 2019/2/7

Y1 - 2019/2/7

N2 - DNA sequences called retrotransposons can copy themselves and reintegrate at new sites in the genome, causing damage. It now seems that inhibiting this process can prevent age-related health decline in mice.

AB - DNA sequences called retrotransposons can copy themselves and reintegrate at new sites in the genome, causing damage. It now seems that inhibiting this process can prevent age-related health decline in mice.

KW - Ageing

KW - Molecular biology

KW - Physiology

UR - http://www.scopus.com/inward/record.url?scp=85061140940&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85061140940&partnerID=8YFLogxK

U2 - 10.1038/d41586-018-07553-0

DO - 10.1038/d41586-018-07553-0

M3 - Article

C2 - 30728507

AN - SCOPUS:85061140940

SN - 0028-0836

VL - 566

SP - 46

EP - 48

JO - Nature

JF - Nature

IS - 7742

ER -

Inhibition of ‘jumping genes’ promotes healthy ageing

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this