Inherited renal carcinomas

Akira Kawashima, Scott W. Young, Naoki Takahashi, Bernard Francis King, Thomas D. Atwell

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

Hereditary forms of kidney carcinoma account for 5–8% of all malignant kidney neoplasms. The renal tumors are often multiple and bilateral and occur at an earlier age. Each of the hereditary kidney carcinoma syndromes is associated with specific gene mutations as well as a specific histologic type of kidney carcinoma. The presence of associated extrarenal manifestations may suggest a hereditary kidney cancer syndrome. Radiology is most commonly used to screen and manage patients with hereditary kidney cancer syndromes. This manuscript reviews the clinical and imaging findings of well-defined inherited kidney cancer syndromes including von Hippel–Lindau disease, Birt–Hogg–Dubé syndrome, hereditary papillary renal carcinoma syndrome, hereditary leiomyomatosis and RCC syndrome, tuberous sclerosis complex, and Lynch syndrome.

Original languageEnglish (US)
Pages (from-to)1-13
Number of pages13
JournalAbdominal Radiology
DOIs
StateAccepted/In press - Apr 23 2016

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Keywords

  • Birt–Hogg–Dubé
  • Hereditary leiomyomatosis renal cell carcinoma
  • Hereditary papillary renal carcinoma
  • Inherited renal carcinomas
  • Lynch syndrome
  • Tuberous sclerosis complex
  • von Hippel–Lindau

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Gastroenterology
  • Urology
  • Radiological and Ultrasound Technology

Cite this

Kawashima, A., Young, S. W., Takahashi, N., King, B. F., & Atwell, T. D. (Accepted/In press). Inherited renal carcinomas. Abdominal Radiology, 1-13. https://doi.org/10.1007/s00261-016-0743-6