TY - JOUR
T1 - Informing therapeutic lymphadenectomy
T2 - Location of regional metastatic lymph nodes in adrenocortical carcinoma
AU - Sada, Alaa
AU - Glasgow, Amy E.
AU - Lyden, Melanie L.
AU - Dy, Benzon M.
AU - Foster, Trenton R.
AU - Habermann, Elizabeth B.
AU - Bancos, Irina
AU - McKenzie, Travis J.
N1 - Publisher Copyright:
© 2021 Elsevier Inc.
PY - 2022/6
Y1 - 2022/6
N2 - Background: The anatomic boundaries of lymphadenectomy for adrenocortical carcinoma (ACC) are not defined. Methods: Adults undergoing resection of ACC were included. Locations were categorized based on positive LN locations on final pathology. Results: Of 231 resected ACC, 6% had positive LN during initial resection. Positive LN in left ACC (n = 7) were: 2 para-aortic, 2 left renal-hilar, 1 para-aortic and left renal-hilar and 1 unknown, while for right ACC (n = 7): 2 para-caval, 1 para-caval and right renal-hilar, 1 inter-aortocaval, 1 celiac, 1 para-aortic, and 1 unknown. Of 55 resections for recurrent ACC, positive LN in left ACC (n = 2) were: 1 para-aortic, and 1 para-aortic with left renal-hilar, while LN for right ACC (n = 7): 2 inter-aortocaval, 2 right renal-hilar, 2 para-caval and one retrocrural. Conclusion: The most common LN metastases are para-caval for right, and para-aortic and left renal-hilar for left ACC. Further studies are necessary to determine the boundaries of lymphadenectomy in ACC resection.
AB - Background: The anatomic boundaries of lymphadenectomy for adrenocortical carcinoma (ACC) are not defined. Methods: Adults undergoing resection of ACC were included. Locations were categorized based on positive LN locations on final pathology. Results: Of 231 resected ACC, 6% had positive LN during initial resection. Positive LN in left ACC (n = 7) were: 2 para-aortic, 2 left renal-hilar, 1 para-aortic and left renal-hilar and 1 unknown, while for right ACC (n = 7): 2 para-caval, 1 para-caval and right renal-hilar, 1 inter-aortocaval, 1 celiac, 1 para-aortic, and 1 unknown. Of 55 resections for recurrent ACC, positive LN in left ACC (n = 2) were: 1 para-aortic, and 1 para-aortic with left renal-hilar, while LN for right ACC (n = 7): 2 inter-aortocaval, 2 right renal-hilar, 2 para-caval and one retrocrural. Conclusion: The most common LN metastases are para-caval for right, and para-aortic and left renal-hilar for left ACC. Further studies are necessary to determine the boundaries of lymphadenectomy in ACC resection.
KW - Adrenocortical carcinoma
KW - Lymph nodes
KW - Lymphadenectomy
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U2 - 10.1016/j.amjsurg.2021.10.014
DO - 10.1016/j.amjsurg.2021.10.014
M3 - Article
C2 - 34696848
AN - SCOPUS:85117683223
SN - 0002-9610
VL - 223
SP - 1042
EP - 1045
JO - American journal of surgery
JF - American journal of surgery
IS - 6
ER -