Influence of recipient atrial contraction on left ventricular filling dynamics of the transplanted heart assessed by Doppler echocardiography

Hannah A. Valantine, Christopher P. Appleton, Liv K. Hatle, Sharon A. Hunt, Edward B. Stinson, Richard L. Popp

Research output: Contribution to journalArticle

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Abstract

Recipient atrial remnants retain electrical and mechanical activity after orthotopic cardiac transplantation. This study investigated the influence of recipient atrial contraction timing on Doppler ultrasound mitral flow velocity curves, isovolumic relaxation time, peak early mitral flow velocity (M1), mitral valve pressure half-time and peak mitral flow velocity due to atrial systole (M2). Clearly identifiable recipient atrial electrical activity (P waves) was present in 7 of 10 patients studied early postoperatively 2 to 6 months (mean 2.5) (early group) and in 20 of 24 patients seen 1 to 11 years (mean 3) after transplantation (late group). Median age and gender distribution were similar in both groups. For analysis of its influence on isovolumic relaxation time, pressure half-time and M1, recipient atrial contraction was classified by its position in the cardiac cycle as early systole, late systole or diastole. For analysis of M2, it was classified as early diastole, late diastole or systole. Compared with its occurrence in diastole, recipient atrial contraction in late systole was associated with a shorter isovolumic relaxation time, shorter pressure half-time and higher M1. In early systole it was associated with a longer pressure half-time and lower M1 than in diastole; isovolumic relaxation time was unchanged. Recipient atrial contraction in early diastole resulted in a lower M2 than in systole, whereas simultaneous contraction of recipient and donor atria in late diastole resulted in an increase in M2. These results indicate that the timing of recipient atrial contraction and relaxation significantly influences left ventricular filling dynamics.

Original languageEnglish (US)
Pages (from-to)1159-1163
Number of pages5
JournalThe American Journal of Cardiology
Volume59
Issue number12
DOIs
StatePublished - May 1 1987
Externally publishedYes

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Doppler Echocardiography
Diastole
Systole
Pressure
Doppler Ultrasonography
Age Distribution
Heart Transplantation
Mitral Valve
Transplantation
Tissue Donors

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Influence of recipient atrial contraction on left ventricular filling dynamics of the transplanted heart assessed by Doppler echocardiography. / Valantine, Hannah A.; Appleton, Christopher P.; Hatle, Liv K.; Hunt, Sharon A.; Stinson, Edward B.; Popp, Richard L.

In: The American Journal of Cardiology, Vol. 59, No. 12, 01.05.1987, p. 1159-1163.

Research output: Contribution to journalArticle

Valantine, Hannah A. ; Appleton, Christopher P. ; Hatle, Liv K. ; Hunt, Sharon A. ; Stinson, Edward B. ; Popp, Richard L. / Influence of recipient atrial contraction on left ventricular filling dynamics of the transplanted heart assessed by Doppler echocardiography. In: The American Journal of Cardiology. 1987 ; Vol. 59, No. 12. pp. 1159-1163.
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