Influence of magnesium on the secretion and action of parathyroid hormone

K Sreekumaran Nair, I. M. Holdaway, M. C. Evans, A. D. Cameron

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

The interactions of serum levels of magnesium and parathyroid hormone (PTH) have been studied in a patient with hypomagnesemia and hypocalcemia following intestinal bypass surgery for obesity. When serum magnesium was low serum PTH was not stimulated by hypocalcemia. With correction of magnesium deficiency hypocalcemia was associated with elevation of serum PTH levels. Infusion of exogenous PTH induced a clearly detectable renal response in the presence of hypomagnesemia but the response was diminished when serum magnesium was elevated. In this patient it appears that hypomagnesemia suppressed parathyroid gland activity leaving the renal action of PTH intact.

Original languageEnglish (US)
Pages (from-to)267-270
Number of pages4
JournalJournal of Endocrinological Investigation
Volume2
Issue number3
StatePublished - 1979
Externally publishedYes

Fingerprint

Parathyroid Hormone
Magnesium
Hypocalcemia
Serum
Jejunoileal Bypass
Magnesium Deficiency
Kidney
Parathyroid Glands
Obesity

ASJC Scopus subject areas

  • Endocrinology

Cite this

Influence of magnesium on the secretion and action of parathyroid hormone. / Nair, K Sreekumaran; Holdaway, I. M.; Evans, M. C.; Cameron, A. D.

In: Journal of Endocrinological Investigation, Vol. 2, No. 3, 1979, p. 267-270.

Research output: Contribution to journalArticle

Nair, K Sreekumaran ; Holdaway, I. M. ; Evans, M. C. ; Cameron, A. D. / Influence of magnesium on the secretion and action of parathyroid hormone. In: Journal of Endocrinological Investigation. 1979 ; Vol. 2, No. 3. pp. 267-270.
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