Inflammatory orbital pseudotumor with extension beyond the orbit

Michael A. Mahr, Diva R. Salomao, James A. Garrity

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

Purpose To summarize the clinical profile and response to treatment of 4 biopsy-proven cases of inflammatory orbital pseudotumor extending beyond the orbit. Design Retrospective observational case series. Methods Four patients' charts were retrospectively reviewed. There were three men with extraorbital extension (two intracranial; one maxillary antrum) and one woman with intracranial disease that extended into the orbit. The men were 40, 41, and 60 years old; the woman was 73 years old. Results Two men with orbital myositis and mild discomfort, initially treated with corticosteroids, had asymptomatic intracranial disease 9 and 12 months after initial presentation. A third man had extension into the maxillary antrum after initial symptoms of painless diplopia. The woman had intraorbital disease with minimal discomfort (dacryoadenitis and myositis) 5 years after presenting with intracranial disease in the Meckel cave that subsequently became bilateral. Histopathologic examination in all cases showed nonspecific inflammation without evidence of vasculitis or granulomas. Conclusions Unlike typical cases of nonspecific orbital inflammation, two of these four cases did not have pain as a prominent feature. Neuroimaging was essential in diagnosing asymptomatic extraorbital disease. Surgery has a prominent role in confirming this diagnosis, primarily by helping to rule out other diseases, such as those with granulomatous inflammation or vasculitis. Additional therapy was usually not required postoperatively.

Original languageEnglish (US)
Pages (from-to)396-400
Number of pages5
JournalAmerican Journal of Ophthalmology
Volume138
Issue number3
DOIs
StatePublished - Sep 2004

Fingerprint

Orbital Pseudotumor
Orbit
Asymptomatic Diseases
Maxillary Sinus
Vasculitis
Inflammation
Orbital Myositis
Dacryocystitis
Myositis
Diplopia
Granuloma
Neuroimaging
Adrenal Cortex Hormones
Biopsy
Pain
Therapeutics

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Inflammatory orbital pseudotumor with extension beyond the orbit. / Mahr, Michael A.; Salomao, Diva R.; Garrity, James A.

In: American Journal of Ophthalmology, Vol. 138, No. 3, 09.2004, p. 396-400.

Research output: Contribution to journalArticle

Mahr, Michael A. ; Salomao, Diva R. ; Garrity, James A. / Inflammatory orbital pseudotumor with extension beyond the orbit. In: American Journal of Ophthalmology. 2004 ; Vol. 138, No. 3. pp. 396-400.
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