Inflammatory causes of gastroparesis: Report of five cases

H. Pande, Brian E. Lacy, M. D. Crowell

Research output: Contribution to journalArticle

21 Scopus citations

Abstract

Gastroparesis is a disorder of delayed gastric emptying. It can be defined as the impaired transit of intraluminal contents from the stomach to the duodenum in the absence of mechanical obstruction. The etiologies of gastroparesis are multiple and diverse. Common known causes include long-standing diabetes mellitus, prior gastric surgery with Or without vagotomy, collagen vascular disorders, pseudoobstruction, medications, and viral infections. Idiopathic gastroparesis still accounts for one third of all cases (1), although some of these patients may have had a preceding, albeit unrecognized, viral illness. Symptoms of gastroparesis are nonspecific and include early satiety, nausea, anorexia, abdominal pain, bloating, and weight loss. Two additional symptoms that correlate well with the presence of gastroparesis are vomiting and postprandial fullness (2). In this report we describe a series of five cases of gastroparesis; three of which developed after vaccination and two of which occurred after the development of Lyme disease. We believe these are the first such reported cases in the medical literature. These cases raise the possibility that inflammatory conditions may produce gastroparesis.

Original languageEnglish (US)
Pages (from-to)2664-2668
Number of pages5
JournalDigestive Diseases and Sciences
Volume47
Issue number12
DOIs
StatePublished - Dec 1 2002

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Keywords

  • Anthrax
  • Gastroparesis
  • Hepatitis B
  • Lyme disease
  • Tetanus
  • Vaccines

ASJC Scopus subject areas

  • Physiology
  • Gastroenterology

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