TY - JOUR
T1 - Inflammatory causes of gastroparesis
T2 - Report of five cases
AU - Pande, H.
AU - Lacy, Brian E.
AU - Crowell, M. D.
PY - 2002/12/1
Y1 - 2002/12/1
N2 - Gastroparesis is a disorder of delayed gastric emptying. It can be defined as the impaired transit of intraluminal contents from the stomach to the duodenum in the absence of mechanical obstruction. The etiologies of gastroparesis are multiple and diverse. Common known causes include long-standing diabetes mellitus, prior gastric surgery with Or without vagotomy, collagen vascular disorders, pseudoobstruction, medications, and viral infections. Idiopathic gastroparesis still accounts for one third of all cases (1), although some of these patients may have had a preceding, albeit unrecognized, viral illness. Symptoms of gastroparesis are nonspecific and include early satiety, nausea, anorexia, abdominal pain, bloating, and weight loss. Two additional symptoms that correlate well with the presence of gastroparesis are vomiting and postprandial fullness (2). In this report we describe a series of five cases of gastroparesis; three of which developed after vaccination and two of which occurred after the development of Lyme disease. We believe these are the first such reported cases in the medical literature. These cases raise the possibility that inflammatory conditions may produce gastroparesis.
AB - Gastroparesis is a disorder of delayed gastric emptying. It can be defined as the impaired transit of intraluminal contents from the stomach to the duodenum in the absence of mechanical obstruction. The etiologies of gastroparesis are multiple and diverse. Common known causes include long-standing diabetes mellitus, prior gastric surgery with Or without vagotomy, collagen vascular disorders, pseudoobstruction, medications, and viral infections. Idiopathic gastroparesis still accounts for one third of all cases (1), although some of these patients may have had a preceding, albeit unrecognized, viral illness. Symptoms of gastroparesis are nonspecific and include early satiety, nausea, anorexia, abdominal pain, bloating, and weight loss. Two additional symptoms that correlate well with the presence of gastroparesis are vomiting and postprandial fullness (2). In this report we describe a series of five cases of gastroparesis; three of which developed after vaccination and two of which occurred after the development of Lyme disease. We believe these are the first such reported cases in the medical literature. These cases raise the possibility that inflammatory conditions may produce gastroparesis.
KW - Anthrax
KW - Gastroparesis
KW - Hepatitis B
KW - Lyme disease
KW - Tetanus
KW - Vaccines
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U2 - 10.1023/A:1021036601462
DO - 10.1023/A:1021036601462
M3 - Article
C2 - 12498282
AN - SCOPUS:0036911874
SN - 0163-2116
VL - 47
SP - 2664
EP - 2668
JO - Digestive diseases and sciences
JF - Digestive diseases and sciences
IS - 12
ER -