Inflammatory bowel disease in the elderly

Syed Wasif Hussain, Darrell S. Pardi

Research output: Contribution to journalReview article

21 Scopus citations

Abstract

Although inflammatory bowel disease (IBD) is generally considered a disease of young adults, it can occur in elderly individuals. The clinical features and treatment considerations in older patients are similar to those in younger patients, with some notable exceptions, which are reviewed in this article. Consideration of appropriate differential diagnoses is critical in older IBD patients to achieve the correct diagnosis and appropriate therapy. The risks associated with use of some IBD medications may be increased in older patients, but so is the risk of under-treated IBD and surgery. Therefore, in older IBD patients, as in younger patients, a thorough understanding of the indications, contraindications, and potential adverse effects of the various medications used to treat the condition is essential.

Original languageEnglish (US)
Pages (from-to)617-624
Number of pages8
JournalDrugs and Aging
Volume27
Issue number8
DOIs
StatePublished - 2010

Keywords

  • azathioprine
  • ciclosporin
  • corticosteroids
  • crohns-disease
  • elderly
  • hydrocortisone
  • inflammatory-bowel-diseases
  • infliximab
  • mercaptopurine
  • mesalazine
  • methotrexate
  • prednisone
  • therapeutic use
  • treatment
  • tumour-necrosis-factor-inhibitors
  • ulcerative-colitis

ASJC Scopus subject areas

  • Geriatrics and Gerontology
  • Pharmacology (medical)

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