Infections of cardiovascular implantable electronic devices and VAD

M. Rizwan Sohail, James M. Steckelberg

Research output: Chapter in Book/Report/Conference proceedingChapter


Cardiovascular implantable electronic devices (CIED) include permanent pacemakers (PPM), implantable cardioverter-defibrillators (ICD), and cardiac resynchronization therapy (CRT) devices. The reported risk of CIED infection ranges from 1% to 10% and depends on the complexity of the device and host comorbid conditions. Once infected, patients need to undergo complete device removal and systemic antibiotic therapy to achieve cure. Earlier versions of CIEDs required surgical placement of epicardial leads, which was facilitated by sternotomy, and generators were mostly placed in the abdominal area. However, in contemporary practice, most device leads are placed percutaneously via the subclavian vein and the device generator resides in a subcutaneous pocket in the pectoral area. Use of epicardial leads is now reserved for special situations where transvenous lead placement is not possible or deemed high risk due to active or recent bloodstream infection.

Original languageEnglish (US)
Title of host publicationClinical Infectious Disease, Second Edition
PublisherCambridge University Press
Number of pages6
ISBN (Electronic)9781139855952
ISBN (Print)9781107038912
StatePublished - Jan 1 2015

ASJC Scopus subject areas

  • Medicine(all)


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