Infection associated with prosthetic joints

Jose L. Del Pozo, Robin Patel

Research output: Contribution to journalArticle

472 Citations (Scopus)

Abstract

A 62-year-old woman with osteoarthritis presents with a 7-month history of progressively worsening left hip pain radiating to the groin, 8 months after undergoing total left-hip arthroplasty. The pain has not responded to nonsteroidal antiinflammatory drugs. Physical examination reveals a sinus tract overlying her left hip. Her leukocyte count is 8000 per cubic millimeter, and the C-reactive protein (CRP) level is 15.5 mg per liter. A radiograph shows loosening of the prosthesis at the bone-cement interface. Synovial-fluid aspirate shows 15×103 cells per cubic millimeter (89% neutrophils); cultures of an aspirate from the hip grow Staphylococcus epidermidis. How should her case be managed?

Original languageEnglish (US)
Pages (from-to)787-794
Number of pages8
JournalNew England Journal of Medicine
Volume361
Issue number8
DOIs
StatePublished - Aug 20 2009

Fingerprint

Hip
Joints
Infection
Prosthesis Failure
Pain
Bone Cements
Staphylococcus epidermidis
Groin
Synovial Fluid
Leukocyte Count
Osteoarthritis
Arthroplasty
C-Reactive Protein
Physical Examination
Neutrophils
Anti-Inflammatory Agents
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Infection associated with prosthetic joints. / Del Pozo, Jose L.; Patel, Robin.

In: New England Journal of Medicine, Vol. 361, No. 8, 20.08.2009, p. 787-794.

Research output: Contribution to journalArticle

Del Pozo, Jose L. ; Patel, Robin. / Infection associated with prosthetic joints. In: New England Journal of Medicine. 2009 ; Vol. 361, No. 8. pp. 787-794.
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