Stem cells are present throughout the lifespan. Naturally derived stem cells include embryonic stem cells, perinatal stem cells, and adult stem cells [1-8]. These endogenous pools of stem cells provide the foundation for cardiovascular development in utero and tissue renewal throughout adulthood [9-11]. Beyond natural sources of stem cells that are limited by availability, immune intolerance, and lineage specification, bioengineered stem cell platforms are rapidly being developed for regenerative medicine applications. This chapter provides an overview of the current state of the art for induced pluripotent stem (iPS) cells and highlights the emerging techniques available to image the transformation of ordinary cells into stem cell counterparts that have acquired the ability to functionally repair the damaged heart.
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- Physics and Astronomy(all)