Individualized kV selection and tube current reduction in excretory phase computed tomography urography: potential for radiation dose reduction and the contribution of iterative reconstruction to image quality.

Adam T. Froemming, Akira Kawashima, Naoki M Takahashi, Robert P. Hartman, Mark A. Nathan, Rickey E. Carter, Lifeng Yu, Shuai Leng, Hiroki Kagoshima, Cynthia H McCollough, Joel Garland Fletcher

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Abstract

The objective of this study was to analyze radiation dose reduction and image quality by combining automated kV selection, tube current reduction, and iterative reconstruction. This was a retrospective analysis of the excretory phase of 55 patients with 2 computed tomography urography examinations: automated kV selection with tube current reduction ("low-dose protocol": with filtered back projection vs iterative reconstruction) and routine dose examinations. Image quality was analyzed blindly and in side-by-side analyses, in addition to quantitative measurements. Low-dose protocol median dose change was -40% (-10.7 to +12.9 mGy); 100 kV was autoselected in 44 (80%) of 55 patients (body mass index range, 19-36 kg/m) with mean dose reduction of 42.5%. Whereas up to 19% of low-dose images with filtered back projection were inferior by blinded review (P < 0.001), low-dose iterative reconstruction images were not rated inferior (P = 1.0). The combination of iterative reconstruction, automated kV selection, and tube current reduction results in radiation dose reduction with preserved image quality and diagnostic confidence.

Original languageEnglish (US)
Pages (from-to)551-559
Number of pages9
JournalJournal of Computer Assisted Tomography
Volume37
Issue number4
StatePublished - Jul 2013

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Computer-Assisted Image Processing
Urography
Tomography
Radiation
Body Mass Index

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

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title = "Individualized kV selection and tube current reduction in excretory phase computed tomography urography: potential for radiation dose reduction and the contribution of iterative reconstruction to image quality.",
abstract = "The objective of this study was to analyze radiation dose reduction and image quality by combining automated kV selection, tube current reduction, and iterative reconstruction. This was a retrospective analysis of the excretory phase of 55 patients with 2 computed tomography urography examinations: automated kV selection with tube current reduction ({"}low-dose protocol{"}: with filtered back projection vs iterative reconstruction) and routine dose examinations. Image quality was analyzed blindly and in side-by-side analyses, in addition to quantitative measurements. Low-dose protocol median dose change was -40{\%} (-10.7 to +12.9 mGy); 100 kV was autoselected in 44 (80{\%}) of 55 patients (body mass index range, 19-36 kg/m) with mean dose reduction of 42.5{\%}. Whereas up to 19{\%} of low-dose images with filtered back projection were inferior by blinded review (P < 0.001), low-dose iterative reconstruction images were not rated inferior (P = 1.0). The combination of iterative reconstruction, automated kV selection, and tube current reduction results in radiation dose reduction with preserved image quality and diagnostic confidence.",
author = "Froemming, {Adam T.} and Akira Kawashima and Takahashi, {Naoki M} and Hartman, {Robert P.} and Nathan, {Mark A.} and Carter, {Rickey E.} and Lifeng Yu and Shuai Leng and Hiroki Kagoshima and McCollough, {Cynthia H} and Fletcher, {Joel Garland}",
year = "2013",
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language = "English (US)",
volume = "37",
pages = "551--559",
journal = "Journal of Computer Assisted Tomography",
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T1 - Individualized kV selection and tube current reduction in excretory phase computed tomography urography

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AU - Froemming, Adam T.

AU - Kawashima, Akira

AU - Takahashi, Naoki M

AU - Hartman, Robert P.

AU - Nathan, Mark A.

AU - Carter, Rickey E.

AU - Yu, Lifeng

AU - Leng, Shuai

AU - Kagoshima, Hiroki

AU - McCollough, Cynthia H

AU - Fletcher, Joel Garland

PY - 2013/7

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