TY - JOUR
T1 - Individualized kV selection and tube current reduction in excretory phase computed tomography urography
T2 - potential for radiation dose reduction and the contribution of iterative reconstruction to image quality.
AU - Froemming, Adam T.
AU - Kawashima, Akira
AU - Takahashi, Naoki
AU - Hartman, Robert P.
AU - Nathan, Mark A.
AU - Carter, Rickey E.
AU - Yu, Lifeng
AU - Leng, Shuai
AU - Kagoshima, Hiroki
AU - McCollough, Cynthia H.
AU - Fletcher, Joel G.
PY - 2013/1/1
Y1 - 2013/1/1
N2 - The objective of this study was to analyze radiation dose reduction and image quality by combining automated kV selection, tube current reduction, and iterative reconstruction. This was a retrospective analysis of the excretory phase of 55 patients with 2 computed tomography urography examinations: automated kV selection with tube current reduction ("low-dose protocol": with filtered back projection vs iterative reconstruction) and routine dose examinations. Image quality was analyzed blindly and in side-by-side analyses, in addition to quantitative measurements. Low-dose protocol median dose change was -40% (-10.7 to +12.9 mGy); 100 kV was autoselected in 44 (80%) of 55 patients (body mass index range, 19-36 kg/m) with mean dose reduction of 42.5%. Whereas up to 19% of low-dose images with filtered back projection were inferior by blinded review (P < 0.001), low-dose iterative reconstruction images were not rated inferior (P = 1.0). The combination of iterative reconstruction, automated kV selection, and tube current reduction results in radiation dose reduction with preserved image quality and diagnostic confidence.
AB - The objective of this study was to analyze radiation dose reduction and image quality by combining automated kV selection, tube current reduction, and iterative reconstruction. This was a retrospective analysis of the excretory phase of 55 patients with 2 computed tomography urography examinations: automated kV selection with tube current reduction ("low-dose protocol": with filtered back projection vs iterative reconstruction) and routine dose examinations. Image quality was analyzed blindly and in side-by-side analyses, in addition to quantitative measurements. Low-dose protocol median dose change was -40% (-10.7 to +12.9 mGy); 100 kV was autoselected in 44 (80%) of 55 patients (body mass index range, 19-36 kg/m) with mean dose reduction of 42.5%. Whereas up to 19% of low-dose images with filtered back projection were inferior by blinded review (P < 0.001), low-dose iterative reconstruction images were not rated inferior (P = 1.0). The combination of iterative reconstruction, automated kV selection, and tube current reduction results in radiation dose reduction with preserved image quality and diagnostic confidence.
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M3 - Article
C2 - 23863531
AN - SCOPUS:84884325166
VL - 37
SP - 551
EP - 559
JO - American Journal of Physiology - Renal Fluid and Electrolyte Physiology
JF - American Journal of Physiology - Renal Fluid and Electrolyte Physiology
SN - 1931-857X
IS - 4
ER -