Abstract
Objective: The aim of this study was to determine if computed tomography (CT) angiography using an individualized transition delay (CTA-ID) would facilitate reductions in injection rate and iodine dose. Methods: The CTA-ID was performed in 20 patients with routine injection rate and iodine dose; 20 patients with injection rate lowered by 1 mL/s; and 40 patients with injection rate lowered by 1 mL/s with 29% less iodine. Routine CTAs in the same or size-matched patients served as controls. Diagnostic image quality and intra-arterial CT numbers were assessed. Results: The median transition delay between aortic threshold and CTA-ID image acquisition was significantly longer than with conventional bolus tracking (mean increase, 13.3 seconds; P < 0.0001), with image quality being the same or better. Intra-arterial CT numbers were 200 Hounsfield units or greater for 80 of 80 CTA-ID, but not for 6 of 49 (12%) internal control or for 11 of 80 (14%) size-matched control patients. Conclusion: The CTA-ID bolus-tracking software alters transition delays to permit diagnostic CTA examinations despite slower injection rate and less iodine.
Original language | English (US) |
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Pages (from-to) | 612-618 |
Number of pages | 7 |
Journal | Journal of computer assisted tomography |
Volume | 43 |
Issue number | 4 |
DOIs | |
State | Published - Jul 1 2019 |
Keywords
- computed tomography angiography
- iodinated contrast
- population biological variation
- x-ray computed tomography
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging