Individual predisposition to coronary microvascular obstruction

R. Jay Widmer; Amir Lerman

doi:10.1016/B978-0-12-812528-1.00004-X

Individual predisposition to coronary microvascular obstruction

R. Jay Widmer, Amir Lerman

Cardiovascular Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Coronary microvascular obstruction (CMVO) during ST-elevation myocardial infarction can occur in up to half of those presenting to the cardiac catheterization laboratory and undergo percutaneous revascularization. Poor microvascular and endothelial function are known to be associated with CMVO, and are potential avenues for preventative strategies. In this chapter, we highlight the associations between poor microvascular and endothelial function, provide clinical signs and manifestations of poor systemic endothelial and/or microvascular function, and outline some strategies to prevent endothelial and microvascular function.

Original language	English (US)
Title of host publication	Coronary Microvascular Obstruction in Acute Myocardial Infarction
Subtitle of host publication	From Mechanisms to Treatment
Publisher	Elsevier
Pages	69-81
Number of pages	13
ISBN (Electronic)	9780128125281
ISBN (Print)	9780128133613
DOIs	https://doi.org/10.1016/B978-0-12-812528-1.00004-X
State	Published - Jan 1 2018

Keywords

Endothelial dysfunction
Microcirculation
Prevention

ASJC Scopus subject areas

General Medicine

Access to Document

10.1016/B978-0-12-812528-1.00004-X

Cite this

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AU - Lerman, Amir

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AB - Coronary microvascular obstruction (CMVO) during ST-elevation myocardial infarction can occur in up to half of those presenting to the cardiac catheterization laboratory and undergo percutaneous revascularization. Poor microvascular and endothelial function are known to be associated with CMVO, and are potential avenues for preventative strategies. In this chapter, we highlight the associations between poor microvascular and endothelial function, provide clinical signs and manifestations of poor systemic endothelial and/or microvascular function, and outline some strategies to prevent endothelial and microvascular function.

KW - Endothelial dysfunction

KW - Microcirculation

KW - Prevention

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M3 - Chapter

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SP - 69

EP - 81

BT - Coronary Microvascular Obstruction in Acute Myocardial Infarction

PB - Elsevier

ER -

Individual predisposition to coronary microvascular obstruction

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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