Individual data pooled analyses to improve understanding of adjuvant therapy in colon cancer: Review of the ACCENT collaborative group

Sharlene Gill, Daniel J. Sargent

Research output: Contribution to journalReview article

1 Scopus citations

Abstract

The Adjuvant Colon Cancer Endpoints (ACCENT) Group is an international, collaborative, individual-patient data analysis now including 20,898 patients enrolled in 18 adjuvant therapy trials for resected stage II and stage III colon cancer, spanning the years 1977 to 1999. This article discusses the proceedings published and presented since the inception of the ACCENT Group in 2003, which notably include the evaluation of 3-year disease-free survival as an acceptable end point in adjuvant studies, particularly in stage III colon cancer, and an improved understanding of the time-dependent patterns of failure and benefi t of adjuvant therapy.

Original languageEnglish (US)
Pages (from-to)155-159
Number of pages5
JournalCurrent Colorectal Cancer Reports
Volume4
Issue number3
DOIs
StatePublished - Jul 1 2008

ASJC Scopus subject areas

  • Hepatology
  • Oncology
  • Gastroenterology

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