Increasing Health Care Burden of Chronic Liver Disease Compared With Other Chronic Diseases, 2004–2013

Sumeet K. Asrani, Maria Kouznetsova, Gerald Ogola, Thomas Taylor, Andrew Masica, Brandon Pope, James Trotter, Patrick Sequeira Kamath, Fasiha Kanwal

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Background & Aims: Chronic liver disease (CLD) is a common and expensive condition, and studies of CLD-related hospitalizations have underestimated the true burden of disease. We analyzed data from a large, diverse health care system to compare time trends in CLD-related hospitalizations with those in congestive heart failure (CHF) or chronic obstructive pulmonary disease (COPD). Methods: We collected data from a large health care system in Texas on hospitalizations related to CLD (n = 27,783), CHF (n = 60,415), and COPD (n = 34,199) from January 1, 2004 through December 31, 2013. We calculated annual hospitalization rates (per 100,000) and compared hospital course, inpatient mortality, ancillary services, and readmissions. Results: Compared with patients with CHF (median age, 71 years) or COPD (median age, 69 years), patients with CLD were significantly younger (median age, 57 years) (P <.01 vs CHF and COPD). Higher proportions of patients with CLD were uninsured (11.7% vs 5.4% for CHF and 5.4% for COPD, P <.01) and Hispanic (17% for CLD vs 9.3% for CHF and 5.0% for COPD, P <.01). A lower proportion of patients with CLD had Medicare (41.5% vs 68.6% with CHF and 70.1% with COPD, P <.01). From 2004 through 2013, the rate of CLD-related hospitalization increased by 92% (from 1295/100,000 to 2490/100,000), compared with 6.7% for CHF (from 3843/100,000 to 4103/100,000) and 48.8% for COPD (from 1775/100,000 to 2642/100,000). During this time period, CLD-related hospitalizations covered by Medicare increased from 31.8% to 41.5%, whereas hospitalizations covered by Medicare did not change for CHF (remained at 70%) or COPD (remained at 70%). Patients with CLD had longer hospital stays (7.3 days vs 6.2 days for CHF and 5.9 days for COPD, P <.01). A higher proportion of patients with CLD died or were discharged to hospice (14.2% vs 11.5% of patients with CHF and 9.3% of patients with COPD, P <.01), and a smaller proportion had access to postacute care (13.2% vs 23.2% of patients with CHF and 27.4% of patients with COPD, P <.01). A higher proportion of patients with CLD were readmitted to the hospital within 30 days (25% vs 21.9% of patients with CHF and 20.6% with COPD, P <.01). Conclusions: Patients with CLD, compared with selected other chronic diseases, had increasing rates of hospitalization, longer hospital stays, more readmissions, and, despite these adverse outcomes, less access to postacute care. Disease management models for CLD are greatly needed to manage the anticipated increase in hospitalizations for CLD.

Original languageEnglish (US)
Pages (from-to)719-729.e4
JournalGastroenterology
Volume155
Issue number3
DOIs
StatePublished - Sep 1 2018

Fingerprint

Liver Diseases
Chronic Disease
Chronic Obstructive Pulmonary Disease
Delivery of Health Care
Heart Failure
Hospitalization
Subacute Care
Medicare
Length of Stay
Hospices
Disease Management
Hispanic Americans
Inpatients

Keywords

  • Cirrhosis
  • Epidemiology
  • Temporal
  • Trend

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Asrani, S. K., Kouznetsova, M., Ogola, G., Taylor, T., Masica, A., Pope, B., ... Kanwal, F. (2018). Increasing Health Care Burden of Chronic Liver Disease Compared With Other Chronic Diseases, 2004–2013. Gastroenterology, 155(3), 719-729.e4. https://doi.org/10.1053/j.gastro.2018.05.032

Increasing Health Care Burden of Chronic Liver Disease Compared With Other Chronic Diseases, 2004–2013. / Asrani, Sumeet K.; Kouznetsova, Maria; Ogola, Gerald; Taylor, Thomas; Masica, Andrew; Pope, Brandon; Trotter, James; Kamath, Patrick Sequeira; Kanwal, Fasiha.

In: Gastroenterology, Vol. 155, No. 3, 01.09.2018, p. 719-729.e4.

Research output: Contribution to journalArticle

Asrani, SK, Kouznetsova, M, Ogola, G, Taylor, T, Masica, A, Pope, B, Trotter, J, Kamath, PS & Kanwal, F 2018, 'Increasing Health Care Burden of Chronic Liver Disease Compared With Other Chronic Diseases, 2004–2013', Gastroenterology, vol. 155, no. 3, pp. 719-729.e4. https://doi.org/10.1053/j.gastro.2018.05.032
Asrani, Sumeet K. ; Kouznetsova, Maria ; Ogola, Gerald ; Taylor, Thomas ; Masica, Andrew ; Pope, Brandon ; Trotter, James ; Kamath, Patrick Sequeira ; Kanwal, Fasiha. / Increasing Health Care Burden of Chronic Liver Disease Compared With Other Chronic Diseases, 2004–2013. In: Gastroenterology. 2018 ; Vol. 155, No. 3. pp. 719-729.e4.
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abstract = "Background & Aims: Chronic liver disease (CLD) is a common and expensive condition, and studies of CLD-related hospitalizations have underestimated the true burden of disease. We analyzed data from a large, diverse health care system to compare time trends in CLD-related hospitalizations with those in congestive heart failure (CHF) or chronic obstructive pulmonary disease (COPD). Methods: We collected data from a large health care system in Texas on hospitalizations related to CLD (n = 27,783), CHF (n = 60,415), and COPD (n = 34,199) from January 1, 2004 through December 31, 2013. We calculated annual hospitalization rates (per 100,000) and compared hospital course, inpatient mortality, ancillary services, and readmissions. Results: Compared with patients with CHF (median age, 71 years) or COPD (median age, 69 years), patients with CLD were significantly younger (median age, 57 years) (P <.01 vs CHF and COPD). Higher proportions of patients with CLD were uninsured (11.7{\%} vs 5.4{\%} for CHF and 5.4{\%} for COPD, P <.01) and Hispanic (17{\%} for CLD vs 9.3{\%} for CHF and 5.0{\%} for COPD, P <.01). A lower proportion of patients with CLD had Medicare (41.5{\%} vs 68.6{\%} with CHF and 70.1{\%} with COPD, P <.01). From 2004 through 2013, the rate of CLD-related hospitalization increased by 92{\%} (from 1295/100,000 to 2490/100,000), compared with 6.7{\%} for CHF (from 3843/100,000 to 4103/100,000) and 48.8{\%} for COPD (from 1775/100,000 to 2642/100,000). During this time period, CLD-related hospitalizations covered by Medicare increased from 31.8{\%} to 41.5{\%}, whereas hospitalizations covered by Medicare did not change for CHF (remained at 70{\%}) or COPD (remained at 70{\%}). Patients with CLD had longer hospital stays (7.3 days vs 6.2 days for CHF and 5.9 days for COPD, P <.01). A higher proportion of patients with CLD died or were discharged to hospice (14.2{\%} vs 11.5{\%} of patients with CHF and 9.3{\%} of patients with COPD, P <.01), and a smaller proportion had access to postacute care (13.2{\%} vs 23.2{\%} of patients with CHF and 27.4{\%} of patients with COPD, P <.01). A higher proportion of patients with CLD were readmitted to the hospital within 30 days (25{\%} vs 21.9{\%} of patients with CHF and 20.6{\%} with COPD, P <.01). Conclusions: Patients with CLD, compared with selected other chronic diseases, had increasing rates of hospitalization, longer hospital stays, more readmissions, and, despite these adverse outcomes, less access to postacute care. Disease management models for CLD are greatly needed to manage the anticipated increase in hospitalizations for CLD.",
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T1 - Increasing Health Care Burden of Chronic Liver Disease Compared With Other Chronic Diseases, 2004–2013

AU - Asrani, Sumeet K.

AU - Kouznetsova, Maria

AU - Ogola, Gerald

AU - Taylor, Thomas

AU - Masica, Andrew

AU - Pope, Brandon

AU - Trotter, James

AU - Kamath, Patrick Sequeira

AU - Kanwal, Fasiha

PY - 2018/9/1

Y1 - 2018/9/1

N2 - Background & Aims: Chronic liver disease (CLD) is a common and expensive condition, and studies of CLD-related hospitalizations have underestimated the true burden of disease. We analyzed data from a large, diverse health care system to compare time trends in CLD-related hospitalizations with those in congestive heart failure (CHF) or chronic obstructive pulmonary disease (COPD). Methods: We collected data from a large health care system in Texas on hospitalizations related to CLD (n = 27,783), CHF (n = 60,415), and COPD (n = 34,199) from January 1, 2004 through December 31, 2013. We calculated annual hospitalization rates (per 100,000) and compared hospital course, inpatient mortality, ancillary services, and readmissions. Results: Compared with patients with CHF (median age, 71 years) or COPD (median age, 69 years), patients with CLD were significantly younger (median age, 57 years) (P <.01 vs CHF and COPD). Higher proportions of patients with CLD were uninsured (11.7% vs 5.4% for CHF and 5.4% for COPD, P <.01) and Hispanic (17% for CLD vs 9.3% for CHF and 5.0% for COPD, P <.01). A lower proportion of patients with CLD had Medicare (41.5% vs 68.6% with CHF and 70.1% with COPD, P <.01). From 2004 through 2013, the rate of CLD-related hospitalization increased by 92% (from 1295/100,000 to 2490/100,000), compared with 6.7% for CHF (from 3843/100,000 to 4103/100,000) and 48.8% for COPD (from 1775/100,000 to 2642/100,000). During this time period, CLD-related hospitalizations covered by Medicare increased from 31.8% to 41.5%, whereas hospitalizations covered by Medicare did not change for CHF (remained at 70%) or COPD (remained at 70%). Patients with CLD had longer hospital stays (7.3 days vs 6.2 days for CHF and 5.9 days for COPD, P <.01). A higher proportion of patients with CLD died or were discharged to hospice (14.2% vs 11.5% of patients with CHF and 9.3% of patients with COPD, P <.01), and a smaller proportion had access to postacute care (13.2% vs 23.2% of patients with CHF and 27.4% of patients with COPD, P <.01). A higher proportion of patients with CLD were readmitted to the hospital within 30 days (25% vs 21.9% of patients with CHF and 20.6% with COPD, P <.01). Conclusions: Patients with CLD, compared with selected other chronic diseases, had increasing rates of hospitalization, longer hospital stays, more readmissions, and, despite these adverse outcomes, less access to postacute care. Disease management models for CLD are greatly needed to manage the anticipated increase in hospitalizations for CLD.

AB - Background & Aims: Chronic liver disease (CLD) is a common and expensive condition, and studies of CLD-related hospitalizations have underestimated the true burden of disease. We analyzed data from a large, diverse health care system to compare time trends in CLD-related hospitalizations with those in congestive heart failure (CHF) or chronic obstructive pulmonary disease (COPD). Methods: We collected data from a large health care system in Texas on hospitalizations related to CLD (n = 27,783), CHF (n = 60,415), and COPD (n = 34,199) from January 1, 2004 through December 31, 2013. We calculated annual hospitalization rates (per 100,000) and compared hospital course, inpatient mortality, ancillary services, and readmissions. Results: Compared with patients with CHF (median age, 71 years) or COPD (median age, 69 years), patients with CLD were significantly younger (median age, 57 years) (P <.01 vs CHF and COPD). Higher proportions of patients with CLD were uninsured (11.7% vs 5.4% for CHF and 5.4% for COPD, P <.01) and Hispanic (17% for CLD vs 9.3% for CHF and 5.0% for COPD, P <.01). A lower proportion of patients with CLD had Medicare (41.5% vs 68.6% with CHF and 70.1% with COPD, P <.01). From 2004 through 2013, the rate of CLD-related hospitalization increased by 92% (from 1295/100,000 to 2490/100,000), compared with 6.7% for CHF (from 3843/100,000 to 4103/100,000) and 48.8% for COPD (from 1775/100,000 to 2642/100,000). During this time period, CLD-related hospitalizations covered by Medicare increased from 31.8% to 41.5%, whereas hospitalizations covered by Medicare did not change for CHF (remained at 70%) or COPD (remained at 70%). Patients with CLD had longer hospital stays (7.3 days vs 6.2 days for CHF and 5.9 days for COPD, P <.01). A higher proportion of patients with CLD died or were discharged to hospice (14.2% vs 11.5% of patients with CHF and 9.3% of patients with COPD, P <.01), and a smaller proportion had access to postacute care (13.2% vs 23.2% of patients with CHF and 27.4% of patients with COPD, P <.01). A higher proportion of patients with CLD were readmitted to the hospital within 30 days (25% vs 21.9% of patients with CHF and 20.6% with COPD, P <.01). Conclusions: Patients with CLD, compared with selected other chronic diseases, had increasing rates of hospitalization, longer hospital stays, more readmissions, and, despite these adverse outcomes, less access to postacute care. Disease management models for CLD are greatly needed to manage the anticipated increase in hospitalizations for CLD.

KW - Cirrhosis

KW - Epidemiology

KW - Temporal

KW - Trend

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