Increased X-ray visualization of shape memory polymer foams by chemical incorporation of iodine motifs

Landon D. Nash, Mary Beth Browning Monroe, Yong Hong Ding, Kendal P. Ezell, Anthony J. Boyle, Ramanathan D Kadirvel, David F Kallmes, Duncan J. Maitland

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Shape memory polymers can be programmed into a secondary geometry and recovered to their primary geometry with the application of a controlled stimulus. Porous shape memory polymer foam scaffolds that respond to body temperature show particular promise for embolic medical applications. A limitation for the minimally invasive delivery of these materials is an inherent lack of X-ray contrast. In this work, a triiodobenzene containing a monomer was incorporated into a shape memory polymer foam material system to chemically impart X-ray visibility and increase material toughness. Composition and process changes enabled further control over material density and thermomechanical properties. The proposed material system demonstrates a wide range of tailorable functional properties for the design of embolic medical devices, including X-ray visibility, expansion rate, and porosity. Enhanced visualization of these materials can improve the acute performance of medical devices used to treat vascular malformations, and the material porosity provides a healing scaffold for durable occlusion.

Original languageEnglish (US)
Article number381
JournalPolymers
Volume9
Issue number8
DOIs
StatePublished - Aug 20 2017

Fingerprint

Iodine
Shape memory effect
Foams
Polymers
Visualization
X rays
Scaffolds
Visibility
Porosity
Geometry
Medical applications
Toughness
Monomers
Chemical analysis

Keywords

  • Medical device
  • Polymer foam
  • Shape memory polymer

ASJC Scopus subject areas

  • Chemistry(all)
  • Polymers and Plastics

Cite this

Nash, L. D., Monroe, M. B. B., Ding, Y. H., Ezell, K. P., Boyle, A. J., Kadirvel, R. D., ... Maitland, D. J. (2017). Increased X-ray visualization of shape memory polymer foams by chemical incorporation of iodine motifs. Polymers, 9(8), [381]. https://doi.org/10.3390/polym9080381

Increased X-ray visualization of shape memory polymer foams by chemical incorporation of iodine motifs. / Nash, Landon D.; Monroe, Mary Beth Browning; Ding, Yong Hong; Ezell, Kendal P.; Boyle, Anthony J.; Kadirvel, Ramanathan D; Kallmes, David F; Maitland, Duncan J.

In: Polymers, Vol. 9, No. 8, 381, 20.08.2017.

Research output: Contribution to journalArticle

Nash, Landon D. ; Monroe, Mary Beth Browning ; Ding, Yong Hong ; Ezell, Kendal P. ; Boyle, Anthony J. ; Kadirvel, Ramanathan D ; Kallmes, David F ; Maitland, Duncan J. / Increased X-ray visualization of shape memory polymer foams by chemical incorporation of iodine motifs. In: Polymers. 2017 ; Vol. 9, No. 8.
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