Abstract
A detergent insoluble 58 000 D polypeptide is phosphorylated at an increased rate during mitotic arrest in cultured Chinese hamster ovary cells. Using one-dimensional peptide mapping, this polypeptide was identified as a phosphorylated form of intermediate filament protein (IFP). The increased rate of phosphorylation is observed with either colcemid- or vinblastine-treated mitotic cells, but is not seen with similarly treated interphase cells.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 445-449 |
| Number of pages | 5 |
| Journal | Experimental Cell Research |
| Volume | 133 |
| Issue number | 2 |
| DOIs | |
| State | Published - 1981 |
| Externally published | Yes |
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Cite this
Increased phosphorylation rate of intermediate filaments during mitotic arrest. / Robinson, Sabina I.; Nelkin, Barry; Kaufmann, Scott H; Vogelstein, Bert.
In: Experimental Cell Research, Vol. 133, No. 2, 1981, p. 445-449.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Increased phosphorylation rate of intermediate filaments during mitotic arrest
AU - Robinson, Sabina I.
AU - Nelkin, Barry
AU - Kaufmann, Scott H
AU - Vogelstein, Bert
PY - 1981
Y1 - 1981
N2 - A detergent insoluble 58 000 D polypeptide is phosphorylated at an increased rate during mitotic arrest in cultured Chinese hamster ovary cells. Using one-dimensional peptide mapping, this polypeptide was identified as a phosphorylated form of intermediate filament protein (IFP). The increased rate of phosphorylation is observed with either colcemid- or vinblastine-treated mitotic cells, but is not seen with similarly treated interphase cells.
AB - A detergent insoluble 58 000 D polypeptide is phosphorylated at an increased rate during mitotic arrest in cultured Chinese hamster ovary cells. Using one-dimensional peptide mapping, this polypeptide was identified as a phosphorylated form of intermediate filament protein (IFP). The increased rate of phosphorylation is observed with either colcemid- or vinblastine-treated mitotic cells, but is not seen with similarly treated interphase cells.
UR - http://www.scopus.com/inward/record.url?scp=0019503532&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0019503532&partnerID=8YFLogxK
U2 - 10.1016/0014-4827(81)90338-4
DO - 10.1016/0014-4827(81)90338-4
M3 - Article
C2 - 7195343
AN - SCOPUS:0019503532
VL - 133
SP - 445
EP - 449
JO - Experimental Cell Research
JF - Experimental Cell Research
SN - 0014-4827
IS - 2
ER -