Increased Bone Marrow Plasma-Cell Percentage Predicts Outcomes in Newly Diagnosed Multiple Myeloma Patients

Abdullah S. Al Saleh, Harsh V. Parmar, Alissa Visram, Eli Muchtar, Francis K. Buadi, Ronald S. Go, Angela Dispenzieri, Prashant Kapoor, Rahma Warsame, Martha Q. Lacy, David Dingli, Nelson Leung, Wilson I. Gonsalves, Taxiarchis V. Kourelis, Morie A. Gertz, Robert A. Kyle, S. Vincent Rajkumar, Shaji K. Kumar

Research output: Contribution to journalArticlepeer-review

Abstract

In the current era, the impact of bone marrow plasma-cell percentage (BMPC%) at diagnosis of multiple myeloma (MM) is not well described. We evaluated the prognostic impact of BMPC% ≥ 60% versus < 60% in 1426 newly diagnosed MM patients. Median progression-free and overall survival were shorter for patients with BMPC% ≥ 60%, even in a multivariate analysis that included known prognostic factors for MM.

Original languageEnglish (US)
Pages (from-to)596-601
Number of pages6
JournalClinical Lymphoma, Myeloma and Leukemia
Volume20
Issue number9
DOIs
StatePublished - Sep 2020

Keywords

  • Outcome
  • Prognosis
  • Tumor burden

ASJC Scopus subject areas

  • Hematology
  • Oncology
  • Cancer Research

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