Inclusion body myositis and renal cell carcinoma. report of two cases and review of the literature

Objective. To describe the clinical course of 2 patients with concurrent inclusion body myositis and renal cell carcinoma and review published reports of inclusion body myositis associated with malignancy. Methods. Prospective followup of 2 patients. Review of published case reports and series of patients with inclusion body myositis. Results. Our 2 patients with inclusion body myositis and renal cell carcinoma had no improvement of strength following nephrectomy. Seven previously reported cases of inclusion body myositis and malignancy were identified and are discussed. Conclusion. Findings in our 2 patients suggest that there is no etiopathologic relationship between inclusion body myositis and malignancy.