Incidence of heart failure after myocardial infarction: Is it changing over time?

Jens P. Hellermann, Tauqir Y. Goraya, Steven J. Jacobsen, Susan A. Weston, Guy S. Reeder, Bernard J. Gersh, Margaret May Redfield, Richard J. Rodeheffer, Barbara P. Yawn, Veronique Lee Roger

Research output: Contribution to journalArticle

107 Citations (Scopus)

Abstract

Improved survival after myocardial infarction (MI) could result in MI survivors' contributing to the US heart failure epidemic. Conversely, since the severity of MI is declining over time, a decline in post-MI heart failure might also be anticipated. This study tested the hypothesis that the incidence of post-MI heart failure was declining over time in a geographically defined MI incidence cohort. Between 1979 and 1994, 1,537 patients with incident MI and no prior history of heart failure were hospitalized in Olmsted County, Minnesota. Framingham Heart Study criteria were used to ascertain the incidence of inpatient and outpatient heart failure over a mean follow-up period of 7.6 years (standard deviation 5.5). Overall, 36% of patients experienced heart failure. After adjustment for factors related to post-MI heart failure (age, hypertension, smoking, and biomarkers), the incidence of heart failure declined by 2% per year (relative risk = 0.98, 95% confidence interval: 0.96, 0.99; p = 0.01). The relative risk of developing heart failure among persons with Mis occurring in 1994 versus 1979 was 0.72 (95% confidence interval: 0.55, 0.93), indicating a 28% reduction in the incidence of heart failure. Administration of reperfusion therapy within 24 hours after MI was associated with lower risk of post-MI heart failure and accounted for most of the temporal decline in heart failure. This suggests that improved survival after MI is unlikely to be a major contributor to the heart failure epidemic.

Original languageEnglish (US)
Pages (from-to)1101-1107
Number of pages7
JournalAmerican Journal of Epidemiology
Volume157
Issue number12
DOIs
StatePublished - Jun 15 2003

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Heart Failure
Myocardial Infarction
Incidence
Confidence Intervals
Survival
Reperfusion
Survivors
Inpatients
Outpatients
Biomarkers
Smoking
Hypertension

Keywords

  • Heart failure, congestive
  • Myocardial infarction

ASJC Scopus subject areas

  • Epidemiology

Cite this

Hellermann, J. P., Goraya, T. Y., Jacobsen, S. J., Weston, S. A., Reeder, G. S., Gersh, B. J., ... Roger, V. L. (2003). Incidence of heart failure after myocardial infarction: Is it changing over time? American Journal of Epidemiology, 157(12), 1101-1107. https://doi.org/10.1093/aje/kwg078

Incidence of heart failure after myocardial infarction : Is it changing over time? / Hellermann, Jens P.; Goraya, Tauqir Y.; Jacobsen, Steven J.; Weston, Susan A.; Reeder, Guy S.; Gersh, Bernard J.; Redfield, Margaret May; Rodeheffer, Richard J.; Yawn, Barbara P.; Roger, Veronique Lee.

In: American Journal of Epidemiology, Vol. 157, No. 12, 15.06.2003, p. 1101-1107.

Research output: Contribution to journalArticle

Hellermann, JP, Goraya, TY, Jacobsen, SJ, Weston, SA, Reeder, GS, Gersh, BJ, Redfield, MM, Rodeheffer, RJ, Yawn, BP & Roger, VL 2003, 'Incidence of heart failure after myocardial infarction: Is it changing over time?', American Journal of Epidemiology, vol. 157, no. 12, pp. 1101-1107. https://doi.org/10.1093/aje/kwg078
Hellermann JP, Goraya TY, Jacobsen SJ, Weston SA, Reeder GS, Gersh BJ et al. Incidence of heart failure after myocardial infarction: Is it changing over time? American Journal of Epidemiology. 2003 Jun 15;157(12):1101-1107. https://doi.org/10.1093/aje/kwg078
Hellermann, Jens P. ; Goraya, Tauqir Y. ; Jacobsen, Steven J. ; Weston, Susan A. ; Reeder, Guy S. ; Gersh, Bernard J. ; Redfield, Margaret May ; Rodeheffer, Richard J. ; Yawn, Barbara P. ; Roger, Veronique Lee. / Incidence of heart failure after myocardial infarction : Is it changing over time?. In: American Journal of Epidemiology. 2003 ; Vol. 157, No. 12. pp. 1101-1107.
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