Incidence of aspiration pneumonia in ALS in Olmsted County, MN

Eric J. Sorenson, Brian Crum, J. Clarke Stevens

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Aspiration pneumonia is believed to be an uncommon complication of amyotrophic lateral sclerosis (ALS). However, the incidence of aspiration pneumonia and its contribution to morbidity and mortality are unknown in ALS. All cases of ALS from Olmsted County, Minnesota from 1990 to 2005 were reviewed. Baseline demographics were noted for all cases. Dates of diagnosis, PEG tube placement, death and survival status were also noted. All cases of aspiration pneumonia were identified. Forty cases of ALS were identified over the 15-year period. The incidence rate was 1.7 cases per 100,000 person years. There was an overall mean survival of 26 months from diagnosis. Aspiration pneumonia occurred in five (13%) cases. There was a mean survival of two months following aspiration pneumonia. The strongest risk factor for aspiration pneumonia was nursing home residence with a relative risk of 7.1 (p = 0.02). We conclude that the incidence rates and demographics of our ALSpopulation have remained stable over time. Aspiration pneumonia occurs in a minority but is associated with a high mortality. ALS subjects residing in nursing homes are at the greatest risk.

Original languageEnglish (US)
Pages (from-to)87-89
Number of pages3
JournalAmyotrophic Lateral Sclerosis
Volume8
Issue number2
DOIs
StatePublished - 2007

Fingerprint

Aspiration Pneumonia
Amyotrophic Lateral Sclerosis
Incidence
Nursing Homes
Survival
Demography
Mortality
Morbidity

Keywords

  • Amyotrophic lateral sclerosis
  • Aspiration pneumonia
  • Epidemiology
  • Percutaneous endoscopic gastrostomy tubes

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

Cite this

Incidence of aspiration pneumonia in ALS in Olmsted County, MN. / Sorenson, Eric J.; Crum, Brian; Stevens, J. Clarke.

In: Amyotrophic Lateral Sclerosis, Vol. 8, No. 2, 2007, p. 87-89.

Research output: Contribution to journalArticle

Sorenson, Eric J. ; Crum, Brian ; Stevens, J. Clarke. / Incidence of aspiration pneumonia in ALS in Olmsted County, MN. In: Amyotrophic Lateral Sclerosis. 2007 ; Vol. 8, No. 2. pp. 87-89.
@article{03f43d7c3d444b1ea84bb8b8d7885655,
title = "Incidence of aspiration pneumonia in ALS in Olmsted County, MN",
abstract = "Aspiration pneumonia is believed to be an uncommon complication of amyotrophic lateral sclerosis (ALS). However, the incidence of aspiration pneumonia and its contribution to morbidity and mortality are unknown in ALS. All cases of ALS from Olmsted County, Minnesota from 1990 to 2005 were reviewed. Baseline demographics were noted for all cases. Dates of diagnosis, PEG tube placement, death and survival status were also noted. All cases of aspiration pneumonia were identified. Forty cases of ALS were identified over the 15-year period. The incidence rate was 1.7 cases per 100,000 person years. There was an overall mean survival of 26 months from diagnosis. Aspiration pneumonia occurred in five (13{\%}) cases. There was a mean survival of two months following aspiration pneumonia. The strongest risk factor for aspiration pneumonia was nursing home residence with a relative risk of 7.1 (p = 0.02). We conclude that the incidence rates and demographics of our ALSpopulation have remained stable over time. Aspiration pneumonia occurs in a minority but is associated with a high mortality. ALS subjects residing in nursing homes are at the greatest risk.",
keywords = "Amyotrophic lateral sclerosis, Aspiration pneumonia, Epidemiology, Percutaneous endoscopic gastrostomy tubes",
author = "Sorenson, {Eric J.} and Brian Crum and Stevens, {J. Clarke}",
year = "2007",
doi = "10.1080/17482960601147461",
language = "English (US)",
volume = "8",
pages = "87--89",
journal = "Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration",
issn = "2167-8421",
publisher = "Informa Healthcare",
number = "2",

}

TY - JOUR

T1 - Incidence of aspiration pneumonia in ALS in Olmsted County, MN

AU - Sorenson, Eric J.

AU - Crum, Brian

AU - Stevens, J. Clarke

PY - 2007

Y1 - 2007

N2 - Aspiration pneumonia is believed to be an uncommon complication of amyotrophic lateral sclerosis (ALS). However, the incidence of aspiration pneumonia and its contribution to morbidity and mortality are unknown in ALS. All cases of ALS from Olmsted County, Minnesota from 1990 to 2005 were reviewed. Baseline demographics were noted for all cases. Dates of diagnosis, PEG tube placement, death and survival status were also noted. All cases of aspiration pneumonia were identified. Forty cases of ALS were identified over the 15-year period. The incidence rate was 1.7 cases per 100,000 person years. There was an overall mean survival of 26 months from diagnosis. Aspiration pneumonia occurred in five (13%) cases. There was a mean survival of two months following aspiration pneumonia. The strongest risk factor for aspiration pneumonia was nursing home residence with a relative risk of 7.1 (p = 0.02). We conclude that the incidence rates and demographics of our ALSpopulation have remained stable over time. Aspiration pneumonia occurs in a minority but is associated with a high mortality. ALS subjects residing in nursing homes are at the greatest risk.

AB - Aspiration pneumonia is believed to be an uncommon complication of amyotrophic lateral sclerosis (ALS). However, the incidence of aspiration pneumonia and its contribution to morbidity and mortality are unknown in ALS. All cases of ALS from Olmsted County, Minnesota from 1990 to 2005 were reviewed. Baseline demographics were noted for all cases. Dates of diagnosis, PEG tube placement, death and survival status were also noted. All cases of aspiration pneumonia were identified. Forty cases of ALS were identified over the 15-year period. The incidence rate was 1.7 cases per 100,000 person years. There was an overall mean survival of 26 months from diagnosis. Aspiration pneumonia occurred in five (13%) cases. There was a mean survival of two months following aspiration pneumonia. The strongest risk factor for aspiration pneumonia was nursing home residence with a relative risk of 7.1 (p = 0.02). We conclude that the incidence rates and demographics of our ALSpopulation have remained stable over time. Aspiration pneumonia occurs in a minority but is associated with a high mortality. ALS subjects residing in nursing homes are at the greatest risk.

KW - Amyotrophic lateral sclerosis

KW - Aspiration pneumonia

KW - Epidemiology

KW - Percutaneous endoscopic gastrostomy tubes

UR - http://www.scopus.com/inward/record.url?scp=34247277733&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34247277733&partnerID=8YFLogxK

U2 - 10.1080/17482960601147461

DO - 10.1080/17482960601147461

M3 - Article

C2 - 17453635

AN - SCOPUS:34247277733

VL - 8

SP - 87

EP - 89

JO - Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

JF - Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

SN - 2167-8421

IS - 2

ER -