TY - JOUR
T1 - Incidence, correlates, management, and clinical outcome of coronary perforation
T2 - Analysis of 16,298 procedures
AU - Fasseas, Panayotis
AU - Orford, James L.
AU - Panetta, Carmelo J.
AU - Bell, Malcolm R.
AU - Denktas, Ali E.
AU - Lennon, Ryan J.
AU - Holmes, David R.
AU - Berger, Peter B.
N1 - Copyright:
Copyright 2018 Elsevier B.V., All rights reserved.
PY - 2004/1
Y1 - 2004/1
N2 - Background: Coronary perforation is a serious but uncommon complication of percutaneous coronary intervention (PCI) and is associated with significant morbidity and mortality. Methods: We performed an analysis of the Mayo Clinic PCI database. Clinical records, procedural reports, and angiographic studies were reviewed. Multiple logistic regression analysis was performed to identify clinical, procedural, anatomic, and angiographic correlates of coronary perforation. Results: A total of 16,298 PCI procedures were performed between January 1990 and December 2001. We identified 95 coronary perforations (0.58%; 95% CI, 0.47-0.71). The incidence of coronary perforation varied with time. Correlates of coronary perforation included the use of an atheroablative device and female sex. Twelve patients (12.6%) sustained an acute myocardial infarction, and cardiac tamponade developed in 11 patients (11.6%). Management strategies included reversal of heparin, pericardiocentesis, placement of a covered stent, and surgical repair. Seven patients died (7.4%). Conclusions: Coronary perforation during PCI is rare, but is associated with significant morbidity and mortality. The variable frequency of perforation may be explained by temporal variations in the use of atheroablative devices.
AB - Background: Coronary perforation is a serious but uncommon complication of percutaneous coronary intervention (PCI) and is associated with significant morbidity and mortality. Methods: We performed an analysis of the Mayo Clinic PCI database. Clinical records, procedural reports, and angiographic studies were reviewed. Multiple logistic regression analysis was performed to identify clinical, procedural, anatomic, and angiographic correlates of coronary perforation. Results: A total of 16,298 PCI procedures were performed between January 1990 and December 2001. We identified 95 coronary perforations (0.58%; 95% CI, 0.47-0.71). The incidence of coronary perforation varied with time. Correlates of coronary perforation included the use of an atheroablative device and female sex. Twelve patients (12.6%) sustained an acute myocardial infarction, and cardiac tamponade developed in 11 patients (11.6%). Management strategies included reversal of heparin, pericardiocentesis, placement of a covered stent, and surgical repair. Seven patients died (7.4%). Conclusions: Coronary perforation during PCI is rare, but is associated with significant morbidity and mortality. The variable frequency of perforation may be explained by temporal variations in the use of atheroablative devices.
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U2 - 10.1016/S0002-8703(03)00505-2
DO - 10.1016/S0002-8703(03)00505-2
M3 - Article
C2 - 14691432
AN - SCOPUS:0346156028
SN - 0002-8703
VL - 147
SP - 140
EP - 145
JO - American heart journal
JF - American heart journal
IS - 1
ER -