Incidence and clinical characteristics of ocular infections after heart transplantation: A retrospective cohort study

Jose L. Del Pozo, Diederik van de Beek, Richard C. Daly, Jose S. Pulido, Christopher G.A. McGregor, Robin Patel

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

Background: Ocular infections associated with organ transplantation are well documented following renal and liver transplantation; however, few studies have reported ocular infections following heart transplant. Methods: We retrospectively studied patients who underwent heart transplantation in the Mayo Clinic Cardiac Transplant Program from January 1st 1988 through June 30th 2006. Results: We report the frequency and type of ocular infections among 313 heart transplant recipients. There were eight patients (2.5%) diagnosed with ocular infections including three cases of ophthalmic zoster, one case of cytomegalovirus retinitis, one case of Aspergillus fumigatus endophthalmitis, one case of Haemophilus influenzae conjunctivitis, one case of blepharitis, and one case of preseptal orbital cellulitis. Conclusions: Ocular infections are rare after heart transplantation and usually present within the first year post-transplantation. The majority can be regarded as opportunistic infections which may be indicative of infections at other body sites. Ocular infections after heart transplantation may be associated with significant morbidity and visual loss if not promptly diagnosed.

Original languageEnglish (US)
Pages (from-to)484-489
Number of pages6
JournalClinical Transplantation
Volume23
Issue number4
DOIs
StatePublished - Aug 14 2009

Keywords

  • Aspergillus infection
  • Cytomegalovirus
  • Heart transplantation
  • Ocular infection
  • Opportunistic infection

ASJC Scopus subject areas

  • Transplantation

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