Incidence and clinical characteristics of congenital nasolacrimal duct obstruction

Saraniya Sathiamoorthi, Ryan D. Frank, Brian G. Mohney

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Background/aims: The literature on the prevalence and demographics of congenital nasolacrimal duct obstruction (CNLDO) is 30-70 years old and largely comprises small sample sizes. This study provides epidemiological findings of this common disorder from the largest cohort reported to date. Methods: The medical records of all children (<5 years of age) residing in Olmsted County, Minnesota, when diagnosed with CNLDO from 1 January 1995 through 31 December 2004, were reviewed. Results: Of 17 713 newborns born during the 10-year study period, 1998 were diagnosed with CNLDO, yielding a birth prevalence of one in nine live births. The diagnosis was made in approximately 90% by a primary care physician, at a median age of 5 weeks, with no gender predilection. Compared with the reference population, CNLDO was associated with premature birth (p=0.005) and was more prevalent among Caucasians (p<0.001). Two-thirds of patients initially presented with discharge alone, 18% with tearing alone and 15% with both discharge and tearing. Conclusions: In this large population-based cohort, CNLDO occurred in one in nine live births with no gender predilection. Prematurity and Caucasian race were associated with the development of CNLDO. Mucopurulent discharge was a much more common feature than tearing at initial presentation.

Original languageEnglish (US)
JournalBritish Journal of Ophthalmology
DOIs
StateAccepted/In press - Jun 6 2018

Fingerprint

Nasolacrimal Duct
Incidence
Live Birth
Premature Birth
Primary Care Physicians
Sample Size
Population
Medical Records
Epidemiologic Studies
Demography
Parturition
Newborn Infant

Keywords

  • Child health (paediatrics)
  • Epidemiology
  • Lacrimal drainage

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

Cite this

Incidence and clinical characteristics of congenital nasolacrimal duct obstruction. / Sathiamoorthi, Saraniya; Frank, Ryan D.; Mohney, Brian G.

In: British Journal of Ophthalmology, 06.06.2018.

Research output: Contribution to journalArticle

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