In vivo measurements of viscoelasticity of the swine heart using Shearwave Dispersionc Ultrasound Vibrometry (SDUV)

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Abstract

Quantification of the viscoelastic properties of the myocardium using ultrasound may aid with evaluation of the health of the heart. Shearwave Dispersion Ultrasound Vibrometry (SDUV) is a method that uses dispersion, or variation with frequency, of shear wave velocities to characterize the underlying viscoelastic material properties of soft tissue. We studied eight pigs in an open-chest preparation, using a mechanical actuator to create harmonic, propagating mechanical waves in the myocardial wall. The motion was tracked using a high frame rate acquisition sequence, typically 2500 Hz, with a Sonix RP system. The velocities of wave propagation were measured over the range 50-350 Hz in 50 Hz increments. Data were acquired over several cardiac cycles. Dispersion curves were fit with a viscoelastic, asymmetrical Lamb wave model to obtain estimates of the shear elasticity, 1, and viscosity, 2. We found excellent agreement between the elastic term measured by SDUV and the shear elastic modulus measured by pressure-segment length analysis. We demonstrated that SDUV measurements and Lamb wave theory allow us to estimate the variation of viscoelastic moduli of the myocardial walls in vivo throughout the course of the cardiac cycle.

Original languageEnglish (US)
Title of host publication2010 IEEE International Ultrasonics Symposium, IUS 2010
Pages686-689
Number of pages4
DOIs
StatePublished - Dec 1 2010
Event2010 IEEE International Ultrasonics Symposium, IUS 2010 - San Diego, CA, United States
Duration: Oct 11 2010Oct 14 2010

Publication series

NameProceedings - IEEE Ultrasonics Symposium
ISSN (Print)1051-0117

Other

Other2010 IEEE International Ultrasonics Symposium, IUS 2010
CountryUnited States
CitySan Diego, CA
Period10/11/1010/14/10

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Keywords

  • Lamb waves
  • heart
  • shear waves
  • viscoelasticity

ASJC Scopus subject areas

  • Acoustics and Ultrasonics

Cite this

Urban, M. W., Pislaru, C., Kinnick, R. R., & Greenleaf, J. F. (2010). In vivo measurements of viscoelasticity of the swine heart using Shearwave Dispersionc Ultrasound Vibrometry (SDUV). In 2010 IEEE International Ultrasonics Symposium, IUS 2010 (pp. 686-689). [5935764] (Proceedings - IEEE Ultrasonics Symposium). https://doi.org/10.1109/ULTSYM.2010.5935764