In vivo examination of lentigo maligna and malignant melanoma in situ, lentigo maligna type by near-infrared reflectance confocal microscopy: Comparison of in vivo confocal images with histologic sections

Zeina S. Tannous, Martin C. Mihm, Thomas J Flotte, Salvador González

Research output: Contribution to journalArticle

99 Citations (Scopus)

Abstract

In vivo confocal microscopy can noninvasively image thin en face sections within living intact human tissue with high resolution and contrast. This evolving technique may provide clinicians with tools to help detect lentigo maligna lesion progression in vivo and may be important in defining tumor margins, thus providing a more definitive surgical eradication of lentigo maligna and malignant melanoma in situ, lentigo maligna type. We present a case of malignant melanoma in situ, lentigo maligna type, and we describe the images seen with confocal microscopy in correlation with routine histopathology.

Original languageEnglish (US)
Pages (from-to)260-263
Number of pages4
JournalJournal of the American Academy of Dermatology
Volume46
Issue number2
DOIs
StatePublished - 2002
Externally publishedYes

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Hutchinson's Melanotic Freckle
Confocal Microscopy
Melanoma
Neoplasms

ASJC Scopus subject areas

  • Dermatology

Cite this

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abstract = "In vivo confocal microscopy can noninvasively image thin en face sections within living intact human tissue with high resolution and contrast. This evolving technique may provide clinicians with tools to help detect lentigo maligna lesion progression in vivo and may be important in defining tumor margins, thus providing a more definitive surgical eradication of lentigo maligna and malignant melanoma in situ, lentigo maligna type. We present a case of malignant melanoma in situ, lentigo maligna type, and we describe the images seen with confocal microscopy in correlation with routine histopathology.",
author = "Tannous, {Zeina S.} and Mihm, {Martin C.} and Flotte, {Thomas J} and Salvador Gonz{\'a}lez",
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language = "English (US)",
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journal = "Journal of the American Academy of Dermatology",
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T1 - In vivo examination of lentigo maligna and malignant melanoma in situ, lentigo maligna type by near-infrared reflectance confocal microscopy

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AU - Tannous, Zeina S.

AU - Mihm, Martin C.

AU - Flotte, Thomas J

AU - González, Salvador

PY - 2002

Y1 - 2002

N2 - In vivo confocal microscopy can noninvasively image thin en face sections within living intact human tissue with high resolution and contrast. This evolving technique may provide clinicians with tools to help detect lentigo maligna lesion progression in vivo and may be important in defining tumor margins, thus providing a more definitive surgical eradication of lentigo maligna and malignant melanoma in situ, lentigo maligna type. We present a case of malignant melanoma in situ, lentigo maligna type, and we describe the images seen with confocal microscopy in correlation with routine histopathology.

AB - In vivo confocal microscopy can noninvasively image thin en face sections within living intact human tissue with high resolution and contrast. This evolving technique may provide clinicians with tools to help detect lentigo maligna lesion progression in vivo and may be important in defining tumor margins, thus providing a more definitive surgical eradication of lentigo maligna and malignant melanoma in situ, lentigo maligna type. We present a case of malignant melanoma in situ, lentigo maligna type, and we describe the images seen with confocal microscopy in correlation with routine histopathology.

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