In vitro renal cortex elasticity and viscosity measurements with Shearwave Dispersion Ultrasound Vibrometry (SDUV) on swine kidney

Carolina Amador, Matthew W. Urban, Lizette V. Warner, James F. Greenleaf

Research output: Chapter in Book/Report/Conference proceedingConference contribution

11 Scopus citations

Abstract

Renal fibrosis threatens kidney viability and fibrosis has been associated with altered tissue structure affecting the biomechanical properties of the kidney, quantifiable as elasticity and viscosity. Importantly, early detection of renal fibrosis may guide therapy and eliminate invasive biopsy procedures. The ability to detect fibrosis early and monitor it regularly with sufficient sensitivity and specificity is an active area of research. A newly emerging method called Shearwave Dispersion Ultrasound Vibrometry (SDUV), that quantifies both elasticity and viscosity by evaluating dispersion of shear wave propagation speed versus its frequency, offers a potential tool to determine renal elasticity and viscosity in vivo. The purpose of this study was to evaluate the feasibility of SDUV for in vitro measurements of renal cortex elasticity and viscosity in the kidney.

Original languageEnglish (US)
Title of host publicationProceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Subtitle of host publicationEngineering the Future of Biomedicine, EMBC 2009
PublisherIEEE Computer Society
Pages4428-4431
Number of pages4
ISBN (Print)9781424432967
DOIs
StatePublished - Jan 1 2009
Event31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009 - Minneapolis, MN, United States
Duration: Sep 2 2009Sep 6 2009

Publication series

NameProceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009

Other

Other31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009
CountryUnited States
CityMinneapolis, MN
Period9/2/099/6/09

ASJC Scopus subject areas

  • Cell Biology
  • Developmental Biology
  • Biomedical Engineering
  • Medicine(all)

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  • Cite this

    Amador, C., Urban, M. W., Warner, L. V., & Greenleaf, J. F. (2009). In vitro renal cortex elasticity and viscosity measurements with Shearwave Dispersion Ultrasound Vibrometry (SDUV) on swine kidney. In Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009 (pp. 4428-4431). [5332750] (Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009). IEEE Computer Society. https://doi.org/10.1109/IEMBS.2009.5332750