In vitro renal cortex elasticity and viscosity measurements with Shearwave Dispersion Ultrasound Vibrometry (SDUV) on swine kidney.

Carolina Amador, Matthew W. Urban, Lizette V. Warner, James F. Greenleaf

Research output: Contribution to journalArticle

Abstract

Renal fibrosis threatens kidney viability and fibrosis has been associated with altered tissue structure affecting the biomechanical properties of the kidney, quantifiable as elasticity and viscosity. Importantly, early detection of renal fibrosis may guide therapy and eliminate invasive biopsy procedures. The ability to detect fibrosis early and monitor it regularly with sufficient sensitivity and specificity is an active area of research. A newly emerging method called Shearwave Dispersion Ultrasound Vibrometry (SDUV), that quantifies both elasticity and viscosity by evaluating dispersion of shear wave propagation speed versus its frequency, offers a potential tool to determine renal elasticity and viscosity in vivo. The purpose of this study was to evaluate the feasibility of SDUV for in vitro measurements of renal cortex elasticity and viscosity in the kidney.

Original languageEnglish (US)
Pages (from-to)4428-4431
Number of pages4
JournalConference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference
StatePublished - 2009
Externally publishedYes

Fingerprint

Viscosity measurement
Elasticity
Viscosity
Swine
Ultrasonics
Kidney
Fibrosis
Biopsy
Shear waves
Wave propagation
Tissue
In Vitro Techniques
Sensitivity and Specificity
Research

ASJC Scopus subject areas

  • Computer Vision and Pattern Recognition
  • Signal Processing
  • Biomedical Engineering
  • Health Informatics

Cite this

@article{64b2c706c7544291bf6994bf2d36229a,
title = "In vitro renal cortex elasticity and viscosity measurements with Shearwave Dispersion Ultrasound Vibrometry (SDUV) on swine kidney.",
abstract = "Renal fibrosis threatens kidney viability and fibrosis has been associated with altered tissue structure affecting the biomechanical properties of the kidney, quantifiable as elasticity and viscosity. Importantly, early detection of renal fibrosis may guide therapy and eliminate invasive biopsy procedures. The ability to detect fibrosis early and monitor it regularly with sufficient sensitivity and specificity is an active area of research. A newly emerging method called Shearwave Dispersion Ultrasound Vibrometry (SDUV), that quantifies both elasticity and viscosity by evaluating dispersion of shear wave propagation speed versus its frequency, offers a potential tool to determine renal elasticity and viscosity in vivo. The purpose of this study was to evaluate the feasibility of SDUV for in vitro measurements of renal cortex elasticity and viscosity in the kidney.",
author = "Carolina Amador and Urban, {Matthew W.} and Warner, {Lizette V.} and Greenleaf, {James F.}",
year = "2009",
language = "English (US)",
pages = "4428--4431",
journal = "Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference",
issn = "1557-170X",
publisher = "Institute of Electrical and Electronics Engineers Inc.",

}

TY - JOUR

T1 - In vitro renal cortex elasticity and viscosity measurements with Shearwave Dispersion Ultrasound Vibrometry (SDUV) on swine kidney.

AU - Amador, Carolina

AU - Urban, Matthew W.

AU - Warner, Lizette V.

AU - Greenleaf, James F.

PY - 2009

Y1 - 2009

N2 - Renal fibrosis threatens kidney viability and fibrosis has been associated with altered tissue structure affecting the biomechanical properties of the kidney, quantifiable as elasticity and viscosity. Importantly, early detection of renal fibrosis may guide therapy and eliminate invasive biopsy procedures. The ability to detect fibrosis early and monitor it regularly with sufficient sensitivity and specificity is an active area of research. A newly emerging method called Shearwave Dispersion Ultrasound Vibrometry (SDUV), that quantifies both elasticity and viscosity by evaluating dispersion of shear wave propagation speed versus its frequency, offers a potential tool to determine renal elasticity and viscosity in vivo. The purpose of this study was to evaluate the feasibility of SDUV for in vitro measurements of renal cortex elasticity and viscosity in the kidney.

AB - Renal fibrosis threatens kidney viability and fibrosis has been associated with altered tissue structure affecting the biomechanical properties of the kidney, quantifiable as elasticity and viscosity. Importantly, early detection of renal fibrosis may guide therapy and eliminate invasive biopsy procedures. The ability to detect fibrosis early and monitor it regularly with sufficient sensitivity and specificity is an active area of research. A newly emerging method called Shearwave Dispersion Ultrasound Vibrometry (SDUV), that quantifies both elasticity and viscosity by evaluating dispersion of shear wave propagation speed versus its frequency, offers a potential tool to determine renal elasticity and viscosity in vivo. The purpose of this study was to evaluate the feasibility of SDUV for in vitro measurements of renal cortex elasticity and viscosity in the kidney.

UR - http://www.scopus.com/inward/record.url?scp=84903860356&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84903860356&partnerID=8YFLogxK

M3 - Article

C2 - 19963830

SP - 4428

EP - 4431

JO - Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference

JF - Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference

SN - 1557-170X

ER -