TY - JOUR
T1 - In vitro activity of tedizolid against linezolid-resistant staphylococci and enterococci
AU - Silva-Del Toro, Stephanie L.
AU - Greenwood-Quaintance, Kerryl E.
AU - Patel, Robin
N1 - Publisher Copyright:
© 2016 Elsevier Inc..
PY - 2016/5/1
Y1 - 2016/5/1
N2 - The tedizolid MIC of 27 clinical isolates of linezolid-resistant staphylococci and enterococci was determined. Tedizolid MICs were ≥1 μg/mL and were 4- to 32-fold lower than those of linezolid. Linezolid resistance mechanisms included G2576T 23S rRNA gene and rplC and rplD mutations.
AB - The tedizolid MIC of 27 clinical isolates of linezolid-resistant staphylococci and enterococci was determined. Tedizolid MICs were ≥1 μg/mL and were 4- to 32-fold lower than those of linezolid. Linezolid resistance mechanisms included G2576T 23S rRNA gene and rplC and rplD mutations.
KW - Antimicrobial resistance
KW - Linezolid resistance
KW - Multidrug resistance
KW - Tedizolid resistance
KW - Vancomycin resistant
UR - http://www.scopus.com/inward/record.url?scp=84959867273&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84959867273&partnerID=8YFLogxK
U2 - 10.1016/j.diagmicrobio.2016.02.008
DO - 10.1016/j.diagmicrobio.2016.02.008
M3 - Article
C2 - 26971179
AN - SCOPUS:84959867273
SN - 0732-8893
VL - 85
SP - 102
EP - 104
JO - Diagnostic Microbiology and Infectious Disease
JF - Diagnostic Microbiology and Infectious Disease
IS - 1
ER -