In vitro activity of oritavancin against planktonic and biofilm states of vancomycin-susceptible and vancomycin-resistant enterococci

Qun Yan, Melissa J. Karau, Robin Patel

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

We tested the in vitro activity of oritavancin against 60 vancomycin-susceptible enterococci (VSE) and 27 vancomycin-resistant enterococci (VRE). The oritavancin MIC ranged from ≤0.002 to 0.5 μg/mL; the minimum biofilm bactericidal concentration ranged from ≤0.002 to 2 μg/mL. Oritavancin has promising in vitro activity against VSE and VRE in both planktonic and biofilm states.

Original languageEnglish (US)
Pages (from-to)348-350
Number of pages3
JournalDiagnostic Microbiology and Infectious Disease
Volume91
Issue number4
DOIs
StatePublished - Aug 2018

Keywords

  • Biofilm
  • Enterococcus faecalis
  • Enterococcus faecium
  • Oritavancin
  • VRE

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

Fingerprint

Dive into the research topics of 'In vitro activity of oritavancin against planktonic and biofilm states of vancomycin-susceptible and vancomycin-resistant enterococci'. Together they form a unique fingerprint.

Cite this