Abstract
BACKGROUND: Angiotensin receptor blockers are antihypertensive medications prescribed by a wide variety of physicians, especially for patients with coexistent diabetes mellitus. Angiotensin receptor blockers, as well as angiotensin-converting enzyme inhibitors, are contraindicated in pregnancy. CASE: We describe the reversal of losartan-induced oligohydramnios at 27 weeks of gestation with subsequent development of fetal thrombosis and possible mechanism of action for this extremely rare in utero complication. CONCLUSION: This theory may help explain the fetal stillbirths in women taking this class of medications during the second and third trimester of pregnancy.
Original language | English (US) |
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Pages (from-to) | 739-740 |
Number of pages | 2 |
Journal | Obstetrics and gynecology |
Volume | 108 |
Issue number | 3 II |
DOIs | |
State | Published - Sep 2006 |
ASJC Scopus subject areas
- Obstetrics and Gynecology