TY - JOUR
T1 - In-transit melanoma
T2 - An individualized approach
AU - Grotz, Travis E.
AU - Mansfield, Aaron S.
AU - Kottschade, Lisa A.
AU - Erickson, Lori A.
AU - Erickson, Lori A.
AU - Markovic, Svetomir N.
AU - Jakub, James W.
PY - 2011/12/1
Y1 - 2011/12/1
N2 - The majority of locoregional recurrences in melanoma occur in the form of intradermal or subcutaneous local or in-transit metastasis. In-transit melanoma represents contamination of the lymphatic space that, if treated, can result in long-term cure in a subset of patients. The management of in-transit metastases is challenging, since the treatments and extent of disease vary greatly based on the number, depth, location, and distribution of lesions, and on their biological behavior. A number of different treatment options exist, but there is no level 1 evidence to guide clinical decision-making. Herein we present our institutional treatment algorithm, which allows for individualization based on the patient's presentation.
AB - The majority of locoregional recurrences in melanoma occur in the form of intradermal or subcutaneous local or in-transit metastasis. In-transit melanoma represents contamination of the lymphatic space that, if treated, can result in long-term cure in a subset of patients. The management of in-transit metastases is challenging, since the treatments and extent of disease vary greatly based on the number, depth, location, and distribution of lesions, and on their biological behavior. A number of different treatment options exist, but there is no level 1 evidence to guide clinical decision-making. Herein we present our institutional treatment algorithm, which allows for individualization based on the patient's presentation.
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M3 - Comment/debate
C2 - 22329185
AN - SCOPUS:84855573786
SN - 0890-9091
VL - 25
JO - ONCOLOGY
JF - ONCOLOGY
IS - 14
M1 - 7
ER -