Improving the outcome of adoptive cell transfer by targeting tumor escape

Karen M. Kaluza, Richard Vile

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

Adoptive T-cell transfer is among the most promising immunotherapies against cancer. To continue increasing the potential of this therapy, our studies focus on the inhibition of tumor recurrence. Recently, we have demonstrated several ways in which combination therapies involving multiple T-cell populations and immunostimulatory chemotherapy can enhance long-term survival.

Original languageEnglish (US)
Article numbere22059
JournalOncoImmunology
Volume2
Issue number1
DOIs
StatePublished - Jan 1 2013

Keywords

  • Adoptive T cell therapy
  • Cyclophosphamide
  • Immunostimulatory chemotherapy
  • Melanoma
  • Tumor escape

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Oncology

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